Leucosialin
| Leucosialin | ||
|---|---|---|
| other names |
Galactoglycoprotein, GALGP, CD43 |
|
| Properties of human protein | ||
| Mass / length primary structure | 400 amino acids , 40,322 Da | |
| Identifier | ||
| External IDs | ||
| Orthologue (human) | ||
| Entrez | 953 | |
| Ensemble | ENSG00000138185 | |
| UniProt | P16150 | |
| Refseq (mRNA) | NM_001098175.1 | |
| Refseq (protein) | NP_001091645.1 | |
| PubMed search |
953
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Leukosialin (synonymous CD43 ) is a surface protein from the group of cell adhesion molecules .
properties
Leukosialin is produced by thymocytes , T lymphocytes , neutrophils , plasma cells and myelomas . It is glycosylated and phosphorylated . Leukosialin presents carbohydrates for selectins . When T-lymphocytes are activated, leukosialin is sorted out from the contact surface with the antigen-presenting cell . It is the most abundant surface protein on the cell surface of T lymphocytes and neutrophils.
Web links
Individual evidence
- ^ TO Moreno-Amaral, E. Gout, C. Danella-Polli, F. Tabarin, P. Lesavre, G. Pereira-da-Silva, NM Thielens, L. Halbwachs-Mecarelli: M-ficolin and leukosialin (CD43): new partners in neutrophil adhesion. In: Journal of leukocyte biology. Volume 91, Number 3, March 2012, pp. 469-474, doi : 10.1189 / jlb.0911460 , PMID 22167719 .