Lymphopenia
| Classification according to ICD-10 | |
|---|---|
| D72.8 | Other specified diseases of leukocyte lympho (zyto) penia |
| ICD-10 online (WHO version 2019) | |
As lymphopenia ( lymphopenia ) is called a lack of lymphocytes in the blood (<1,500 cells / mm).
Lymphopenia can u. a. caused by:
- increased cortisol level (e.g. Cushing's syndrome , corticosteroid therapy, stress ),
- Therapy with cytostatics and immunosuppressants ,
- Hodgkin's disease (malignant changes in the bone marrow )
- Miliary tuberculosis ,
- Measles infection,
- Protein deficiency diet ,
- HIV infection / AIDS (lack of T cells ),
- Yellow fever ,
- SARS ,
- COVID-19 ,
- rare diseases of the immune system including some autoimmune diseases and
- extremely high radiation exposure , as for example with victims of the Chernobyl disaster was the case
- Infection with influenza A virus H1N1 (and other influenza A viruses), often combined with an increase in monocytes ; H1N1 was e.g. B. responsible for the Spanish flu , the H1N1 pandemic 2009/10 and the virus flu in Brazil in 2016
With lymphopenia, the risk of developing viral infections increases due to the lack of lymphocytes .
Individual evidence
- ↑ a b c d e f Gerd Herold : Internal medicine . Cologne 2007.
- ↑ a b c Lymphocyte Diseases Overview (www.lymphozyten-info.de, accessed on September 9, 2016)
- ↑ Neutropenia and Lymphocytopenia (www.msd-manual.de, accessed on September 9, 2016)
- ↑ Respiratory virus infections: Clinical differential diagnosis (www.aerzteblatt.de, Dtsch Arztebl 2003; 100: A 3143-3146 [Issue 48])
- ↑ JF Bermejo-Martin, R. Almansa u. a .: Lymphopenic community acquired pneumonia as signature of severe COVID-19 infection. In: The Journal of Infection. [electronic publication before printing] March 2020, doi : 10.1016 / j.jinf.2020.02.029 , PMID 32145214 .
- ↑ I. Böhm: Quantification of absolute peripheral white blood cells and their subsets in patients with lupus erythematosus. In: Biomed Pharmacother . 2006; 60 (2), pp. 92-95.
- ↑ G. Merekoulias, EC Alexopoulos, T. Belezos, E. Panagiotopoulou, DM Jelastopulu: Lymphocyte to monocyte ratio as a screening tool for influenza. In: PLoS currents. Volume 2, 2010, p. RRN1154, PMID 20383263 , PMC 2847387 (free full text).
- ↑ Over 1,000 Deaths from H1N1 Outbreak in Brazil ( Memento of the original from September 11, 2016 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. (Article of July 12, 2016)
