Malignant vascular tumors

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Malignant vascular tumors (MVT) comprise a variety of histopathologically defined sarcomas . These tumors are very rare and can occur in any part of the body. The prognosis is u. a. depending on the location. The large sarcoma registers show that around 7.6% of soft tissue sarcomas can be assigned to MVT. Women and men are affected about equally often.

The different histopathological sub-forms are:

Malignant vascular tumors are to be distinguished from sarcomas with primary vascular involvement (e.g. leiomyosarcoma of the vena cava or vena cava or the aorta or retroperitoneum or extremities) and from sarcomas with secondary vascular involvement.

Symptoms include swelling , pain , tumor protrusion, bleeding , weight loss, or other discomfort. The tumors can occur in different parts of the human body ( limbs , trunk , abdomen , retroperitoneum , endocrine glands, etc.).

The primary treatment for patients without distant metastases is surgery; the principles of sarcoma surgery must be observed. The chemotherapy and radiation therapy may be more treatment options. The prognosis after operative therapy depends on the primary tumor size and location. The most favorable courses are those in which no organ metastases have yet occurred. A special sub-form are the angiosarcomas of the liver, which require a special therapeutic approach by specialized sarcoma surgeons.

Individual evidence

  1. ↑ C. Leowardi, Y. Hormann et al. a .: Ruptured angiosarcoma of the liver treated by emergency catheter-directed embolization. In: World Journal of Gastroenterology. Volume 12, Number 5, February 2006, pp. 804-808, PMID 16521200 , PMC 4066137 (free full text) (review).
  2. ↑ M. Schwarzbach, F. Willeke u. a .: [Leiomyosarcoma of the inferior vena cava]. In: German Medical Weekly . Volume 122, Number 14, April 1997, pp. 439-444, doi : 10.1055 / s-2008-1047635 , PMID 9138922 .
  3. ↑ S. Ockert, H. Schumacher u. a .: [Intraluminal mass lesions of the thoracic aorta]. In: The surgeon . Volume 75, Number 12, December 2004, pp. 1215-1220, doi : 10.1007 / s00104-004-0926-5 , PMID 15309267 .
  4. ↑ MH Schwarzbach, Y. Hormann u. a .: Clinical results of surgery for retroperitoneal sarcoma with major blood vessel involvement. In: Journal of Vascular Surgery . Volume 44, number 1, July 2006, pp. 46-55, doi : 10.1016 / j.jvs.2006.03.001 , PMID 16828425 (review).
  5. ↑ MH Schwarzbach, Y. Hormann u. a .: Results of limb-sparing surgery with vascular replacement for soft tissue sarcoma in the lower extremity. In: Journal of Vascular Surgery . Volume 42, Number 1, July 2005, pp. 88-97, doi : 10.1016 / j.jvs.2005.03.017 , PMID 16012457 .