Type I membranoproliferative glomerulonephritis
Classification according to ICD-10 | |
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N00.5 | Diffuse Mesangiocapillary Glomerulonephritis - Membranoproliferative Glomerulonephritis, Types I and III, or onA |
ICD-10 online (WHO version 2019) |
The membranoproliferative glomerulonephritis type I is the most common form of membranoproliferative glomerulonephritis .
The deposits lie between the endothelium and the basement membrane, in contrast to type III not also between the basement membrane and podocytes .
root cause
The disease can occur idiopathically or due to deposits of immune complexes in the kidney, often with hepatitis C , systemic lupus erythematosus , chronic hepatitis B , subacute bacterial endocarditis, and infected shunt .
Occurrence
Women are more often affected than men.
Clinical manifestations
Type I with nephrotic syndrome is a progressive disease that leads to end-stage renal failure in half of those affected within 10 years and in 90% within 20 years .
Other autoimmune diseases can be associated.
Prospect of healing
Early diagnosis and treatment play a big role in the prognosis in children.
literature
- MS Ahmed, CF Wong, H. Shawki, N. Kapoor, BK Pandya: Rapidly deteriorating renal function with membranoproliferative glomerulonephritis Type 1 associated with hepatitis C treated successfully with steroids and antiviral therapy: a case report and review of literature. In: Clinical nephrology. Vol. 69, No. 4, April 2008, pp. 298-301, PMID 18397706 (review).
- RO Gans, LG Feld: Images in clinical medicine. Membranoproliferative glomerulonephritis type 1. In: The New England Journal of Medicine . Vol. 334, No. 6, February 1996, p. 367, doi: 10.1056 / NEJM199602083340605 , PMID 8538708 .
Individual evidence
- ↑ a b c Emedicine Medscape
- ↑ NK Biyikli, I. Gökçe, F. Cakalağoğlu, p Arbak, H. Alpay: The co-existence of membranoproliferative glomerulonephritis type 1 and celiac disease: a case report. In: Pediatric nephrology. Vol. 24, No. 6, June 2009, pp. 1247-1250, doi: 10.1007 / s00467-009-1118-9 , PMID 19184116 .
- ^ Y. Kawasaki, J. Suzuki, R. Nozawa, H. Suzuki: Efficacy of school urinary screening for membranoproliferative glomerulonephritis type 1. In: Archives of disease in childhood. Vol. 86, No. 1, January 2002, pp. 21-25, PMID 11806875 , PMC 1719067 (free full text).