Miotic
A miotic ( plural : miotics ) is a medicine to constrict the pupil ( miosis ). It is used for diagnostic or therapeutic purposes in human and veterinary ophthalmology and belongs to the group of drugs called parasympathomimetics . The pupil constriction is caused by irritation of the sphincter pupillae muscle . With regard to their mode of action, a distinction is made between directly and indirectly acting miotics.
Miotics are mainly used therapeutically in the treatment of glaucoma , although they are usually contraindicated in secondary glaucoma . Diagnostic areas of application are, for example, pharmacodynamic pupil examinations.
Known side effects can include: variable myopia , accommodation spasms , inadequate light adaptability or local pain sensation.
Common miotics include: pilocarpine , acetylcholine , prostigmine , histamine and morphine . These are usually prescription drugs.
See also
literature
- Pschyrembel clinical dictionary. With clinical syndromes and nouns anatomica. = Clinical Dictionary. Edited by the publisher's dictionary editor under the direction of Christoph Zink. 256th, revised edition. de Gruyter, Berlin a. a. 1990, ISBN 3-11-010881-X .
Individual evidence
- ^ Albert J. Augustin: Ophthalmology. 3rd, completely revised and expanded edition. Springer, Berlin a. a. 2007, ISBN 978-3-540-30454-8 .
Web links
- Entry on miotics in the Pharmawiki
- Paul U. Fechner, Klaus D. Teichmann: Medicinal eye therapy. Basics and practice. 4th, completely revised edition. Enke im Thieme-Verlag, Stuttgart et al. 2000, ISBN 3-13-117924-4 . ( limited preview in Google Book search).