Mydriatic

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Right-sided mydriasis after tropicamide administration

A mydriatic ( plural : mydriatic ) is a pupil-expanding ( mydriasis ) drug. Mydriatics are used for diagnostic or therapeutic purposes in ophthalmology (human or veterinary medicine).

Since the Pupillenerweiterer dilator muscle of the pupil sympathetic , the Pupillenverenger sphincter pupillae contrast parasympathetic innervated, can a dilation of the pupil both stimulating by the sympathetic nervous system agents, sympathomimetic , cause as well - often more effective - inflammatory by the parasympathetic nervous system, Parasympatholytics .

For short-term mydriasis for diagnostic purposes, the agents are generally administered locally to the eye. When using parasympatholytic mydriatics, accommodation disorders also occur , since the parasympathetically innervated part of the ciliary muscle is also paralyzed. For this reason, means are preferred, the effect of which occurs quickly and only lasts for a short time, such as. B. tropicamide.

See also

Individual evidence

  1. ^ Siegfried Ebel , Hermann J. Roth (Ed.): Lexicon of Pharmacy. Georg Thieme, Stuttgart a. a. 1987, ISBN 3-13-672201-9 , p. 451.