Shigekazu Nagata

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Shigekazu Nagata ( Japanese 長 田 重 一 , Nagata Shigekazu ; born July 15, 1949 in Ishikawa Prefecture ) is a Japanese molecular biologist who is particularly known for research on apoptosis .

Nagata studied from 1968 at the University of Tokyo , where he received his doctorate in 1977. He then worked as a post-doctoral student at the Institute for Molecular Biology at the University of Zurich with Charles Weissmann . From 1982 he was an assistant professor at the Institute for Medical Science at the University of Tokyo. From 1987 to 1998 he was head of the molecular biology department at the Osaka Bioscience Institute. From 1995 he was Professor of Genetics at the University of Osaka (first at its Medical School, from 2002 at its Graduate School of Frontier Biosciences).

Nagata is known for research into the mechanism of apoptosis .

Around 1980 he was involved in the early cloning of interferon- alpha (among others with Charles Weissmann ), which enabled its mass production by incorporating the isolated genes into bacteria.

Prizes and awards

Web links

Individual evidence

  1. Nagata, Golstein The Fas death factor , Science, Volume 267, 1995, p. 1449, Nagata Apoptosis by death factor - Review , Cell, Volume 88, 1997, pp. 355-365
  2. Nagata, N. Mantei, C. Weissmann The structure of one of the eight or more distinct chromosomal genes for human interferon-alpha , Nature, Volume 287, 1980, pp. 401-8
  3. Nagata, H. Taira, A. Hall et al. a. Synthesis in E. coli of a polypeptide with human leukocyte interferon activity , Nature, Volume 284, 1980, pp. 316-20
  4. Honorary doctorates from the University of Zurich, April 28, 2012 (PDF, 137 kB) at uzh.ch; Retrieved May 1, 2012