Non-coding ribonucleic acid

Non-coding ribonucleic acid ( English non-coding RNA , ncRNA ) is a collective term for ribonucleic acids that are not translated into proteins like mRNA . These include, for example, rRNAs , tRNAs , small RNAs ( miRNAs , siRNAs , piRNAs , snRNAs , snoRNAs ), lncRNAs , antisense RNAs , riboswitches and ribozymes . In eukaryotes, non-coding ribonucleic acid makes up the majority of the RNA formed by transcription ; B. 98%. It has a variety of functions in the cell.

See also

• Non-coding deoxyribonucleic acid

literature

• JS Mattick, IV Makunin: Non-coding RNA. In: Human Molecular Genetics . Volume 15 Spec No 1, April 2006, pp. R17-R29. doi : 10.1093 / hmg / ddl046 . PMID 16651366 . (Review). PDF
• FF Costa: Non-coding RNAs: lost in translation? In: Genes. Volume 386, Number 1-2, January 2007, pp. 1-10. doi : 10.1016 / j.gene.2006.09.028 . PMID 17113247 . (Review).

Individual evidence

1. ↑ T. Derrien, et al .: The Long Non-Coding RNAs: A New (P) layer in the "Dark Matter" . In: Frontiers in genetics . tape 2 , 2011, p. 107 , doi : 10.3389 / fgene.2011.00107 , PMID 22303401 , PMC 3266617 (free full text) - (English).
2. ^ JS Mattick: Non-coding RNAs: the architects of eukaryotic complexity. In: EMBO reports. Volume 2, Number 11, November 2001, pp. 986-991. doi : 10.1093 / embo-reports / kve230 . PMID 11713189 . PMC 1084129 (free full text).