Otenabant

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Structural formula
Otenabant structural formula
General
Non-proprietary name Otenabant
other names

CP-945,598

Molecular formula C 25 H 25 Cl 2 N 7 O 1
External identifiers / databases
CAS number 686344-29-6
PubChem 10052040
ChemSpider 8227602
DrugBank DB11745
Wikidata Q7108517
Drug information
ATC code

A08 AX

Drug class

Anorectics

Mechanism of action

Selective cannabinoid receptor - CB 1 - antagonist

properties
Molar mass 510.4 g · mol -1
safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Otenabant is a drug that should be used as a drug for obesity . However, the pharmaceutical company Pfizer withdrew its approval when problems, in the form of psychiatric side effects, with the structurally similar rimonabant became apparent.

Like rimonabant, Otenabant is a CB 1 receptor antagonist.

Individual evidence

  1. This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
  2. M. Kim: Design, chemical synthesis, and biological evaluation of novel triazolyl analogues of taranabant (MK-0364), a cannabinoid-1 receptor inverse agonist. In: Tetrahedron. Volume 64, number 48, 2008, pp. 10802-10809, doi : 10.1016 / j.tet.2008.09.057 .