Pleural cancer

Classification according to ICD-10
C38.4	Pleural cancer
ICD-10 online (WHO version 2019)

A pleural ( engl. Pleural carcinosis ) is the infestation of the pleura (pleura) with metastasis of a malignant tumor .

description

The cause of a pleural carcinosis is the spread of a tumor ( carcinosis ) to the pleural cavity . This can be done either via subpleural lung metastases or via a lymphangiosis carcinomatosa . In men, bronchial carcinoma (lung cancer) is the most common primary tumor of pleural cancer, while in women it is the second most common after breast cancer (breast cancer).

Pleural cancer usually causes a pleural effusion , which is an abnormal accumulation of fluid ( exudate ) in the pleural cavity. As a result, the affected patients usually have difficulty breathing and their quality of life is severely limited. A pleurectomy , i.e. the partial or complete surgical removal of the pleura, can significantly improve the quality of life in such cases. The pleural effusion can contain both blood and tumor cells.

It is often very difficult to distinguish pleural carcinomas from epithelioid mesotheliomas . Among other things, a diagnosis can be made with immunohistochemistry .

literature

D. Kaiser, C. Bartz: Indications for surgical treatment of pleural carcinosis In: Zentralbl Chir 115/1990; Pp. 1301-6. PMID 2278209

S. Piller: Local chemotherapy of pleural carcinosis and its combination with radiotherapy. In: Advances in the field of X-rays and nuclear medicine, 88/1958, pp. 76-83. PMID 13512476

KM Müller: pleural mesothelioma. Springer, 2005, ISBN 978-3-540-23014-4 , pp. 43-58.

P. Drings: Management of Lung Carcinoma . Springer, 2003, ISBN 3-540-43145-4

Web links

CT and X-rays of pleural carcinomas MeVis Research

Individual evidence

↑ Berthold Jany, Tobias Welte: Pleural effusion in adults - causes, diagnosis and therapy. In: Deutsches Ärzteblatt. Volume 116, No. 21, 2019, pp. 377-385, here: pp. 379 and 381.
↑ D. Kaiser, G. Leschber: Surgical therapy of pleurisy carcinomatosa. In: European Surgery 28/1996, pp. 95-98.
↑ D. Ganten: Molecular medical principles of non-hereditary tumor diseases. Springer, 2002, ISBN 3-540-41577-7 , p. 79

[1] Berthold Jany, Tobias Welte: Pleural effusion in adults - causes, diagnosis and therapy. In: Deutsches Ärzteblatt. Volume 116, No. 21, 2019, pp. 377-385, here: pp. 379 and 381.

[2] D. Kaiser, G. Leschber: Surgical therapy of pleurisy carcinomatosa. In: European Surgery 28/1996, pp. 95-98.

[3] D. Ganten: Molecular medical principles of non-hereditary tumor diseases. Springer, 2002, ISBN 3-540-41577-7 , p. 79