SUNCT syndrome

SUNCT syndrome
ICD-10 code	G44.08
IHS / ICHD-II code	3.3

When SUNCT ( S hort-lasting U nilateral N euralgiform headache with C onjunctival injection and T earing) of the contact trigeminal neuralgia in a similar pain: Single localized attacks around the eyes in the area of the first trigeminal division of stabbing or pulsating quality. In contrast to trigeminal neuralgia, there is almost always reddening of the eye and tearing on the pain side. The typical age of onset is in the 4th to 6th decades of life, but the disease can occur at any age. The SUNCT syndrome is very rare, around 100 cases have been described in the literature so far.

• Duration of pain: 5 to 250 seconds
• Pain frequency: 3 to 200 times a day

Studies on the treatability of the SUNCT syndrome do not exist. Individual case reports in the literature report successes from the administration of lamotrigine , gabapentin , carbamazepine / oxcarbazepine , clomiphene and zonisamide , sometimes in combination. In individual cases, the intravenous administration of lidocaine was successful in the treatment of the SUNCT syndrome.

See also

• Trigeminal autonomic headache disorders

literature

• IHS-ICHD-II 3.3 SUNCT syndrome
• Guideline "Cluster headache and trigeminal autonomic headache" . Published by the guidelines commission of the German Society for Neurology , the German Migraine and Headache Society , the Austrian Society for Neurology , the Swiss Neurological Society and the Professional Association of German Neurologists . Status: May 14, 2015, valid until May 13, 2020.
• Volker Limmroth: headache and facial pain. Schattauer, Stuttgart 2007, ISBN 978-3-7945-2319-1 .
• A. May, S. Evers, G. Brössner, T. Jürgens, AR Gantenbein, V. Malzacher, A. Straube: Guideline for the diagnosis, therapy and prophylaxis of cluster headaches, other trigeminal autonomic headaches, sleep-bound headaches and idiopathic stabbing A headache. - Revised therapy recommendations of the German Migraine and Headache Society in cooperation with the DGN, ÖKSG, SKG. In: Neurology . 35 (3), 2016, pp. 137–151. dmkg.de (PDF)
• H. Göbel, C. Göbel, A. Heinze: Paroxysmal hemicrania and SUNCT . In: pain . tape 25 , no. 6 , December 2011, p. 689-701 , doi : 10.1007 / s00482-011-1108-2 .

Individual evidence

1. ↑ Guideline "Cluster headache and trigeminal autonomic headache" . Published by the guidelines commission of the German Society for Neurology , the German Migraine and Headache Society , the Austrian Society for Neurology , the Swiss Neurological Society and the Professional Association of German Neurologists . Status: May 14, 2015, valid until May 13, 2020.
2. ↑ JM Gutierrez-Garcia: SUNCT syndrome responsive to lamotrigine . In: Headache . tape 42 , no. 8 , September 2002, p. 823-825 , PMID 12390648 .
3. ^ JL Rosselli, JP Karpinski: The role of lamotrigine in the treatment of short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing syndrome . In: Ann Pharmacother . tape 45 , no. 1 , January 2011, p. 108-113 , doi : 10.1345 / aph.1P462 , PMID 21189366 .
4. ↑ M. Marziniak, R. Breyer, S. Evers: SUNCT syndrome successfully Treated with the combination of oxcarbazepine and gabapentin . In: Pain Med . tape 10 , no. 8 , November 2009, p. 1497-1500 , doi : 10.1111 / j.1526-4637.2009.00729.x , PMID 19863743 .
5. ↑ M. Etemadifar, AH Maghzi, M. Ghasemi, A. Chitsaz, M. Kaji Esfahani: Efficacy of gabapentin in the treatment of SUNCT syndrome. In: Cephalalgia . tape 28 , no. December 12 , 2008, pp. 1339-1342 , doi : 10.1111 / j.1468-2982.2008.01673.x , PMID 18727639 .
6. ↑ B. Dora: SUNCT syndrome with dramatic response to oxcarbazepine . In: Cephalalgia . tape 26 , no. 9 , September 2006, p. 1171–1173 , doi : 10.1111 / j.1468-2982.2006.01177.x , PMID 16919074 .
7. ↑ TD Rozen: Complete alleviation of treatment refractory primary SUNCT syndrome with clomiphene citrate (a medicinal deep brain hypothalamic modulator) . In: Cephalalgia . March 2014, doi : 10.1177 / 0333102414527647 , PMID 24662321 .
8. ↑ TD Rozen, JR Saper, FD Sheftell, DW Dodick: Clomiphene citrate as a new treatment for SUNCT: hormonal manipulation for hypothalamic-influenced trigeminal autonomic cephalalgias . In: Headache . tape 45 , no. 6 , June 2005, p. 754-756 , doi : 10.1111 / j.1526-4610.2005.05143_2.x , PMID 15953310 .
9. ↑ M. Ikawa, N. Imai, S. Manaka: A case of SUNCT syndrome responsive to zonisamide . In: Cephalalgia . tape 31 , no. 4 , March 2011, p. 501-503 , doi : 10.1177 / 0333102410387680 , PMID 21036860 .
10. ↑ JA Pareja, AB Caminero, O. Sjaastad: SUNCT Syndrome: diagnosis and treatment . In: CNS Drugs . tape 16 , no. 6 , 2002, pp. 373-383 , doi : 10.2165 / 00023210-200216060-00002 , PMID 12027784 .
11. ↑ MS Matharu, AS Cohen, PJ Goadsby: SUNCT syndrome responsive to intravenous lidocaine . In: Cephalalgia . tape 24 , no. November 11 , 2004, pp. 985-992 , doi : 10.1111 / j.1468-2982.2004.00886.x , PMID 15482363 .
12. ↑ AM Arroyo, XR Durán, MG Beldarrain, A. Pinedo, JC García-Moncó: Response to intravenous lidocaine in a patient with SUNCT syndrome . In: Cephalalgia . tape 30 , no. 1 , January 2010, p. 110-112 , doi : 10.1111 / j.1468-2982.2009.01871.x , PMID 19438923 .

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