Salah-Eddin Al-Batran

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Salah-Eddin Al-Batran, 2017

Salah-Eddin Al-Batran (born March 1, 1970 in Amman , Jordan ) is a German specialist in internal medicine . He has additional qualifications in hematology , oncology , special pain therapy and palliative medicine . Al-Batran is the author and co-author of over 200 papers in the field of cancer research. One of his most important scientific achievements is the development of FLOT therapy for cancers of the stomach and esophagus.

Life

Al-Batran was born in Amman (Jordan) to Palestinian parents, spent his childhood and youth in Saudi Arabia and emigrated to the Federal Republic of Germany at the age of 17 to study medicine at the Ludwig Maximilians University in Munich . He is currently an adjunct professor of internal medicine at the Johann Wolfgang Goethe University in Frankfurt am Main , member of the board of directors of the University Center for Tumor Diseases Frankfurt (UCT) and medical director of the Institute for Clinical-Oncological Research at the Northwest Hospital in Frankfurt (IKF). Al-Batran is the founder of the Institute for Clinical Cancer Research IKF GmbH, a research organization (CRO) specializing in academic studies and the FLOT study group for gastric carcinoma (English: German Gastric Group) and a member of the "Esophagus / Gastric Carcinoma" lead group of the Internist working group Oncology in the German Cancer Society (AIO).

Research areas

Al-Batran conducts clinical research into the treatment of cancer. His main focus is on research into gastric and esophageal cancer through the FLOT regime he developed and the introduction of new approaches to multimodal therapy and, more recently, the integration of immunotherapy. The results of his research work have been incorporated into the national (S3 guidelines) and international (NCCN and ESMO) guidelines for the treatment of cancer diseases.

Publications

The literature and citation database Web of Science shows Salah-Eddin Al-Batran as author or co-author of over 200 scientific articles with an h-index of 51.

Professional article (selection)

  • SE Al-Batran, A. Atmaca, S. Hegewisch-Becker, D. Jaeger, S. Hahnfeld, MJ Rummel, G. Seipelt, A. Rost, JOA Knuth, E. Jaeger: Phase II trial of biweekly infusional fluorouracil, folinic acid, and oxaliplatin in patients with advanced gastric cancer . In: Journal of Clinical Oncology . tape 22 , no. 4 , February 15, 2004, p. 658-663 , doi : 10.1200 / JCO.2004.07.042 .
  • MJ Rummel, SE Al-Batran, SZ Kim, M. Welslau, R. Hecker, D. Kofahl-Krause, KM Josten, H. Durk, A. Rost, M. Neise, U. von Grunhagen, KU Chow, ML Hansmann , D. Hoelzer, PS Mitrou: Bendamustine plus rituximab is effective and has a favorable toxicity profile in the treatment of mantle cell and low-grade non-Hodgkin's lymphoma . In: Journal of Clinical Oncology . tape 23 , no. 15 , May 20, 2005, pp. 3383-3389 , doi : 10.1200 / JCO.2005.08.100 .
  • A. Atmaca, S.-E. Al-Batran, A. Maurer, A. Neumann, T. Heinzel, B. Hentsch, SE Schwarz, S. Hovelmann, M. Goettlicher, A. Knuth, E. Jaeger: Valproic acid (VPA) in patients with refractory advanced cancer : a dose escalating phase I clinical trial . In: British Journal of Cancer . tape 97 , no. 2 , July 10, 2007, p. 177-182 , doi : 10.1038 / sj.bjc.6603851 .
  • Salah-Eddin Al-Batran, Joerg Thomas Hartmann, Stephan Probst, Harald Schmalenberg, Stephan Hollerbach, Ralf Hofheinz, Volker Rethwisch, Gernot Seipelt, Nils Homann, Gerhard Wilhelm, Gunter Schuch, Jan Stoehlmacher, Hans Guenter Derigs, Susanna Hegewisch-Becker, Johannes Grossmann, Claudia Pauligk, Akin Atmaca, Carsten Bokemeyer, Alexander Knuth, Elke Jaeger: Phase III trial in metastatic gastroesophageal adenocarcinoma with fluorouracil, leucovorin plus either oxaliplatin or cisplatin: A study of the Arbeitsgemeinschaft Internistische Onkologie . In: Journal of Clinical Oncology . tape 26 , no. 9 , March 20, 2008, p. 1435-1442 , doi : 10.1200 / JCO.2007.13.9378 .
  • S.-E. Al-Batran, JT Hartmann, R. Hofheinz, N. Homann, V. Rethwisch, S. Probst, J. Stoehlmacher, MR Clemens, R. Mahlberg, M. Fritz, G. Seipelt, M. Sievert, C. Pauligk, A. Atmaca, E. Jaeger: Biweekly fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) for patients with metastatic adenocarcinoma of the stomach or esophagogastric junction: a phase II trial of the Arbeitsgemeinschaft Internistische Onkologie . In: Annals of Oncology . tape 19 , no. November 11 , 2008, pp. 1882-1887 , doi : 10.1093 / annonc / mdn403 .
  • S.-E. Al-Batran, RD Hofheinz, C. Pauligk, H.-G. Kopp, GM Haag, KB Luley, J. Meiler, N. Homann, S. Lorenzen, H. Schmalenberg, S. Probst, M. Koenigsmann, M. Egger, N. Prasnikar, K. Caca, J. Trojan, UM Martens , A. Block, W. Fischbach, R. Mahlberg, M. Clemens, G. Illerhaus, K. Zirlik, DM Behringer, W. Schmiegel, M. Pohl, M. Heike, U. Ronellenfitsch, M. Schuler, WO Bechstein , A. Königsrainer, T. Gaiser, P. Schirmacher, W. Hozaeel, A. Reichart, TO Goetze, M. Sievert, E. Jäger, S. Mönig, A. Tannapfel: Histopathological regression after neoadjuvant docetaxel, oxaliplatin, fluorouracil, and leucovorin versus epirubicin, cisplatin, and fluorouracil or capecitabine in patients with resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4-AIO): results from the phase 2 part of a multicentre, open-label, randomized phase 2/3 trial . In: The Lancet Oncology . tape 17 , no. December 12 , 2016, p. 1697-1708 , doi : 10.1016 / S1470-2045 (16) 30531-9 .
  • Al-Batran SE, Homann N, Pauligk C, Goetze TO, Meiler J, Kasper S, Kopp HG, Mayer F, Haag GM, Luley K, Lindig U, Schmiegel W, Pohl M, Stoehlmacher J, Folprecht G, Probst S, Prasnikar N, Fischbach W, Mahlberg R, Trojan J, Koenigsmann M, Martens UM, Thuss-Patience P, Egger M, Block A, Heinemann V, Illerhaus G, Moehler M, Schenk M, Kullmann F, Behringer DM, Heike M, Pink D, Teschendorf C, Löhr C, Bernhard H, Schuch G, Rethwisch V, von Weikersthal LF, Hartmann JT, Kneba M, Daum S, Schulmann K, Less J, Belle S, Gaiser T, Oduncu FS, Güntner M, Hozaeel W, Reichart A, Jäger E, Kraus T, Mönig S, Bechstein WO, Schuler M, Schmalenberg H, Hofheinz RD; FLOT4-AIO Investigators: Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomized, phase 2/3 trial. Lancet. 2019 May 11; 393 (10184): 1948-1957. doi: 10.1016 / S0140-6736 (18) 32557-1
  • Fuchs CS, Shitara K, Di Bartolomeo M, Lonardi S, Al-Batran SE, Van Cutsem E, Ilson DH, Alsina M, Chau I, Lacy J, Ducreux M, Mendez GA, Alavez AM, Takahari D, Mansoor W, Enzinger PC, Gorbounova V, Wainberg ZA, Hegewisch-Becker S, Ferry D, Lin J, Carlesi R, Das M, Shah MA; RAINFALL Study Group: Ramucirumab with cisplatin and fluoropyrimidine as first-line therapy in patients with metastatic gastric or junctional adenocarcinoma (RAINFALL): a double-blind, randomized, placebo-controlled, phase 3 trial. Lancet Oncol. 2019 Mar; 20 (3): 420-435. doi: 10.1016 / S1470-2045 (18) 30791-5. Epub 2019 Feb 1. Erratum in: Lancet Oncol. 2019 May; 20 (5): e242.

Reference books

  • Salah-Eddin Al-Batran: Practice in the treatment of gastric carcinoma and adenocarcinoma of the esophagogastric junction . 3. Edition. rs media, Regensburg 2011.
  • Salah-Eddin Al-Batran, Ralf-Dieter Hofheinz: Therapy algorithms oncology 2014 . 2nd, revised edition. rs media, Regensburg 2014, ISBN 978-3-00-043470-9 .

Web links

Individual evidence

  1. ↑ Dr. Salah-Eddin Al-Batran from the Northwest Hospital receives an extraordinary professorship on May 21, 2014
  2. ↑ Prof. Dr. med. Salah-Eddin Al-Batran. Institute for Clinical Oncological Research of the Krankenhaus Nordwest GmbH, accessed on August 28, 2017 (CV).
  3. ^ Institute for Clinical Cancer Research. Retrieved February 3, 2020 .
  4. ^ Web of Science. Thomson Reuters , accessed on September 23, 2017 (English, search for author name AL-BATRAN SE ).
personal data
SURNAME Al-Batran, Salah-Eddin
BRIEF DESCRIPTION German specialist in internal medicine, hematology, oncology, special pain therapy and palliative medicine
DATE OF BIRTH March 1, 1970
PLACE OF BIRTH Amman , Jordan