Talecris
| Talecris Biotherapeutics
|
|
|---|---|
 |
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| legal form | Corporation |
| founding | April 1, 2005 |
| Seat | Research Triangle Park , United States |
| management | Larry Stern, Joel Abelson, Thierry Heinrich |
| Number of employees | 4,500 |
| sales | 1.5 billion USD |
| Branch | Pharmaceutical manufacturer ( biotechnological ) |
| Status: 2008 | |
Talecris is an American pharmaceutical company that focuses on the manufacture of plasma products for the treatment of immunodeficiency diseases and lung diseases, including haemophilia. Talecris is based in Research Triangle Park . In 2008 Talecris had approximately 4,500 employees and sales of $ 1.5 billion. Talecris works primarily on the research, development and production technology of plasma-based immunoglobulins.
history
Talecris was spun off on April 1, 2005 from the Bayer Biological Products business unit of Bayer AG . The history of the company in its various forms and names dates back to 1942 when Cutter Laboratories were the first to succeed in fractionating plasma and making the plasma product albumin .
In 1974 the Cutter Laboratories completed their factory in Clayton, North Carolina with a capacity of 375,000 liters and a workforce of 100, after which the company was taken over by Miles Laboratories . Four years later, in 1978, Miles Laboratories was taken over by Bayer AG. Precision Pharma Services ' predecessor company , New York Blood Center (Melville Biologics), with facilities in Melville, New York , was cleared by the FDA in 1980 . In 1992 Bayer AG merged its US companies and formed Miles Inc , which was renamed Bayer Corporation in 1995 . The Melville facility was acquired by Ampersand Ventures in 2001 and renamed Precision Pharma Services .
The first alpha-1 proteinase inhibitor was marketed as early as 1988 with the launch of the drug Prolastin . The Clayton factory achieved a fractionation capacity of 1.9 million liters per year in 1999. In 2001 Bayer BP developed the Western Blot Assay method for the detection of prions. Furthermore, in 2002, the first company to introduce the security packaging Tamper Evident Packaging (TEP) . In addition to the introduction of Gamunex , Bayer BP was the first company to receive FDA recognition in 2004 for its in-house nucleic acid testing (NAT) for the detection of HIV .
In 2005, the company Talecris Biotherapeutics was founded in the USA , taking over the global plasma business of Bayer BP and the entire development and manufacturing capacity of Precision Pharma Services. Talecris received QSEAL certification from the Plasma Protein Therapeutics Association (PPTA). On April 1, 2006, Talecris was also founded in Canada and on December 1 of the same year in Europe. Also in 2006, the company announced the founding of Talecris Plasma Resources for its own production of plasma in plasma centers all over the USA. Prexision Pharma Services was integrated into Talecris Biotherapeutics.
In 2011 Talecris was acquired by the Spanish company Grifols for four billion US dollars.
Research and Development
Talecris invested US $ 120 million in research and development in 2007, although manufacturing costs are around 50 percent due to the complex extraction of blood plasma. Since blood plasma is subject to strict requirements - which not only concern the acquisition by voluntary donors who are not allowed to belong to any risk group, but above all also the post-processing and control to ensure that there are no pathogens in the raw material - Talecris has its own research and research Development platforms established. The active ingredients examined include all plasma components and immunoglobulins that can be obtained from the donor pool. They support and modulate the immune system through various mechanisms of action.
Products
The following Talecris products are approved in Europe:
- Gamunex ( IVIG-C ). Gamunex is also approved in the United States for the treatment of patients with CIDP .
- Prolastin
The following Talecris products are approved in the USA:
- Koate
- Plasbumin
- Thrombates III
- Hypermunes
Individual evidence
- ↑ Spanish buyer set to take over Talecris ( Memento from September 7, 2012 in the web archive archive.today ). In: newsobserver.com. June 2, 2011.