Tanja Gaich

Tanja Gaich (born June 15, 1980 in Salzburg ) is an Austrian chemist ( organic chemistry , organic synthesis).

Tanja Gaich studied molecular biology at the University of Salzburg from 1998 to 2000 and chemistry from 1999 to 2005 at the University of Vienna , where she received her doctorate in 2009 with Johann Mulzer . As a post-doctoral student , she worked with Phil Baran at the Scripps Research Institute in La Jolla until 2010 . Afterwards she was Sofja Kovalevskaja group leader at the Leibniz University Hanover at the chair of Markus Kalesse and from 2015 professor for organic chemistry at the University of Konstanz .

She deals with the total synthesis of complex natural products, including sarpagine , a Rauwolfia alkaloid , and taxol derivatives. She is also looking for starting molecules that can be used for several total syntheses of natural products. Sometimes she takes the synthetic pathways in nature as an example.

She received the dissertation prize of the Society of Austrian Chemists and the Laudimaxima Prize of the University of Vienna for the advancement of women in mathematics and natural sciences. In 2012 she received the Sofja Kovalevskaja Prize of the Alexander von Humboldt Foundation and in 2014 the Chemistry Lecturer Prize of the ADUC and the Chemistry Prize of the Academy of Sciences in Göttingen for outstanding achievements in the total synthesis of complex natural products (laudation). In 2015 she received an ERC Starting Grant, a prize for young scientists in the field of natural products from DECHEMA and the Early Excellence Award in Science from Bayer AG . In an appreciation for the Bayer AG award, it was emphasized that research on the total synthesis of natural products is on the decline, as this usually requires many individual steps and many years of research with an uncertain outcome, often with setbacks to be overcome.

Fonts (selection)

with J. Mulzer: Total Synthesis of (-) - Penifulvin A, an Insecticide with a Dioxafenestrane Skeleton , J. Am. Chem. Soc. 2009, 131 (2), 452-453, doi: 10.1021 / ja8083048 .
with PS Baran: Aiming for the Ideal Synthesis , J. Org. Chem. 2010, 75 (14), 4657-4673, doi: 10.1021 / jo1006812 .
with J. Mulzer: Biomimetic Synthesis of Alkaloids with a Modified Indole Nucleus, in: Erwan Poupon, Bastien Nay (eds.): Biomimetic Organic Synthesis, Volume 1, Wiley-VCH 2011, pp. 149-180
with S. Krüger: Enantioselective, Protecting-Group-Free Total Synthesis of Sarpagine Alkaloids — A Generalized Approach, Angew. Chem. Int. Ed. 2015, 54 (1), 315-317.
with E. Stamp: Cyclohepta [b] indoles: A Privileged Structure Motif in Natural Products and Drug Design, Acc. Chem. Res. 2016, 49 (11), 2390-2402
with R. Eckermann, M. Breunig: Formal Total Synthesis of (±) -Strictamine by [2,3] -Sigmatropic Stevens Rearrangements, Chem. Eur. J. 2017, 23 (16), 3938-3949.
with CKG Gerlinger, S. Krüger: Total Synthesis of Parvineostemonine by Structure Pattern Recognition: A Unified Approach to Stemona and Sarpagine Alkaloids, Chem. Eur. J. 2018, 24 (16), 3994-3997.
with H. Rebmann, CKG Gerlinger: Gram-Scale Total Synthesis of Sarpagine Alkaloids and Non-Natural Derivatives, Chem. Eur. J. 2019, 25 (11), 2704-2707
with F. Schneider, K. Samarin, S. Zanella: Total synthesis of the complex taxane diterpene canataxpropellane, Science 2020, 367 (6478), 676-681.

Web links

Individual evidence

^ Prize from Bayer AG for Gaich

personal data
SURNAME	Gaich, Tanja
BRIEF DESCRIPTION	Austrian chemist
DATE OF BIRTH	June 15, 1980
PLACE OF BIRTH	Salzburg

[1] Prize from Bayer AG for Gaich