Vladimir Sergeyevich Gulevich

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Vladimir Gulevich

Wladimir Sergejewitsch Gulewitsch , Russian Владимир Сергеевич Гулевич (born November 18, 1867 in Ryazan ; † September 6, 1933 in Moscow ) was a Russian biochemist.

Gulewitsch, the son of a school principal, studied at Lomonosov University , where he graduated in 1890 and received his doctorate in medicine in 1896 ( on choline and neurin ). After spending two years in Germany for further training and being a professor at the University of Kharkov in 1899/1900 , he became associate professor in 1901 and full professor in 1904 at Lomonossow University, where he headed the medicinal chemistry department from 1907 and in 1919 was briefly rector. He also established the biochemistry department at the Moscow Medical School for Women and taught organic chemistry at the Business School.

Gulewitsch was the first to isolate carnitine (1905 with RP Krimberg) from muscle tissue and the first to isolate carnosine (1900 with his student Amiradzibi). They also prepared a platinum salt of carnitine and determined the molecular formula, the correct structural formula was found by R. Krimberg the following year. Carnitine is said to have been found around the same time by Friedrich Kutscher in Marburg, who called it Novain. His structural formula was wrong and R. Krimberg soon proved that both are identical. He investigated the specificity of proteolytic enzymes (like trypsin ) by testing them on small molecular weight substrates, and other organic nitrogen compounds like arginine and its biochemistry.

In 1928 he became a member of the Leopoldina and in 1927 a corresponding and in 1929 a full member of the Soviet Academy of Sciences .

Before the First World War he was also one of the editors of Hoppe-Seyler's magazine for physiological chemistry .

Web links

Individual evidence

  1. ↑ Anatoly Bezkorovainy: Carnosine, carnitine, and Vladimir Gulevich . In: Journal of Chemical Education . tape 51 , no. October 10 , 1974, p. 652-654 , doi : 10.1021 / ed051p652 .
  2. ↑ Member entry by Vladimir S. Gulevic at the German Academy of Natural Scientists Leopoldina , accessed on June 7, 2017.
personal data
SURNAME Gulewitsch, Vladimir Sergejewitsch
ALTERNATIVE NAMES Гулевич, Владимир Сергеевич (Russian); Gulevich, Vladimir Sergeevich (English transcription)
BRIEF DESCRIPTION Russian biochemist
DATE OF BIRTH November 18, 1867
PLACE OF BIRTH Ryazan
DATE OF DEATH September 6, 1933
Place of death Moscow