Volhyn fever

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Classification according to ICD-10
A44.8 Other forms of bartonellosis
ICD-10 online (WHO version 2019)

The Volhynian fever or five-day fever (Latin fever quintana seu wolhynica ), also known as protecting grave fever (English trench fever ), Wolhynienfieber and Werner-His's disease , is a by the bacterium Bartonella quintana triggered infectious disease. It is transmitted from person to person by clothes lice ( Pediculus humanus corporis ) and possibly also by head lice .

history

Bartonella quintana (formerly Rickettsia quintana ), the five-day fever pathogen similar to the spotted fever pathogen (more correct according to the sticker: Volhynian five-day fever ), caused major epidemics among the Allied soldiers on the western front during the First World War , which is why the disease is also called "Wolhynian fever" ( to the Ukrainian countryside of Volyn , where the disease first appeared) and received "trench fever". The name Werner His Disease honors the tropical medicine and hygienist Heinrich Werner and the Swiss internist Wilhelm His , who is in German service , who made significant research into the disease in soldiers in the warfare of the First World War.

course

The incubation period is 10–30 days. The disease is characterized by sudden onset of headache , aseptic meningitis , persistent fever with periodic bouts of fever and other unspecific symptoms such as neuralgia - rheumatic joint and leg pain (especially shin pain expressed in the vernacular with the disease name Shin disease ), conjunctivitis and spleen pain out.

Nowadays the B. quintana pathogen plays a role in people infected with HIV. B. quintana has been shown to cause bacillary angiomatosis . Clinically, this disease presents as single or multiple, cutaneous or subcutaneous lesions with a coarse reddish-livid appearance, which can morphologically resemble Kaposi's sarcoma .

treatment

Treatment is with gentamicin and doxycycline or with macrolide antibiotics such as erythromycin and azithromycin .

literature

Individual evidence

  1. For the designation, especially as five-day fever, correct five-day fever, cf. Georg Sticker : Hippokrates: The common diseases first and third book (around the year 434-430 BC). Translated, introduced and explained from the Greek. Johann Ambrosius Barth, Leipzig 1923 (= Classics of Medicine. Volume 29); Unchanged reprint: Central antiquariat of the German Democratic Republic, Leipzig 1968, pp. 118–121.
  2. M. Maurin, D. Raoult: Bartonella (Rochalimaea) quintana infections. In: Clin Microbiol Rev. 3 (1996), pp. 273-292, PMID 8809460 .
  3. a b M. E. Ohl, DH Spach: Bartonella quintana and urban trench fever. In: Clin Infect Dis . 31 (2000), pp. 131-135, PMID 10913410 .
  4. Karl Wurm, AM Walter: Infectious Diseases. 1961, p. 159.
  5. ^ Short biography of Heinrich Werner (in English). In: A dictionary of medical eponyms. Retrieved January 25, 2016 . on the English web page Who Named It
  6. ^ Medicine Online : Keyword: Werner – His disease
  7. ^ Short biography of Wilhelm His (in English). In: A dictionary of medical eponyms. Retrieved January 25, 2016 . on the English web page Who Named It
  8. Brief description of the "Werner His Disease" (in English). In: A dictionary of medical eponyms. Retrieved January 25, 2016 . on the English web page Who Named It
  9. Karl Wurm, AM Walter: Infectious Diseases. In: Ludwig Heilmeyer (ed.): Textbook of internal medicine. Springer-Verlag, Berlin / Göttingen / Heidelberg 1955; 2nd edition, ibid. 1961, pp. 9-223, here: pp. 131 and 159 f.
  10. ^ Marianne Abele-Horn: Antimicrobial Therapy. Decision support for the treatment and prophylaxis of infectious diseases. With the collaboration of Werner Heinz, Hartwig Klinker, Johann Schurz and August Stich, 2nd, revised and expanded edition. Peter Wiehl, Marburg 2009, ISBN 978-3-927219-14-4 , p. 186.