κ-yeast toxin 2

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Potassium channel toxin kappa-KTx 1.2
other names

Kappa-yeastutoxin-2

Mass / length primary structure 23 amino acids , 2,717 Da
Identifier
External IDs
Occurrence
Parent taxon Heterometrus fulvipes

κ-yeast toxin 2 is a toxin from the scorpion Heterometrus fulvipes .

properties

κ-yeast toxin 2 is a protein and scorpion toxin from the scorpion Heterometrus fulvipes , as is κ-yeast toxin 1 . It slows down the activation of various potassium channels . No structurally related proteins are known to the toxins κ-yeastutoxin 1 and 2.

Individual evidence

  1. KN Srinivasan, V. Sivaraja, I. Huys, T. Sasaki, B. Cheng, TK Kumar, K. Sato, J. Tytgat, C. Yu, BC San, S. Ranganathan, HJ Bowie, RM Kini, P. Gopalakrishnakone: kappa-Hefutoxin1, a novel toxin from the scorpion Heterometrus fulvipes with unique structure and function. Importance of the functional diad in potassium channel selectivity. In: The Journal of biological chemistry. Volume 277, Number 33, August 2002, pp. 30040-30047, doi : 10.1074 / jbc.M111258200 , PMID 12034709 .