3-methyluridine

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Structural formula
Structural formula of 3-methyluridine
General
Surname 3-methyluridine
other names
  • m 3 U (short code)
  • N 3 methyluridines
  • 1-β- D -ribofuranosyl-3-methyl-pyrimidine-2,4-dione
  • 1 - [(2 R , 3 R , 4 S , 5 R ) -3,4-dihydroxy-5- (hydroxymethyl) oxolan-2-yl] -3-methyl-pyrimidin-2,4-dione
Molecular formula C 10 H 14 N 2 O 6
External identifiers / databases
CAS number 2140-69-4
PubChem 99592
Wikidata Q70344251
properties
Molar mass 258.23 g mol −1
Physical state

firmly

safety instructions
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

3-methyluridine (m 3 U) is a rare nucleoside and occurs in the rRNA . It consists of β- D- ribofuranose (sugar) and the nucleobase 3-methyluracil . It is a derivative of uridine which is methylated in the 3-position . Base pairing is not possible due to the methylation in the 3-position .

Web links

  • Entry for 3-methyluridines in the Human Metabolome Database (HMDB) , accessed October 14, 2013.
  • Modification Summary of 3-Methyluridine in the Modomics database, accessed January 14, 2014.

Individual evidence

  1. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
  2. ↑ Patrick A. Limbach, Pamela F. Crain, James A. McCloskey: "Summary: the modified nucleosides of RNA", Nucleic Acids Research , 1994 , 22  (12), pp. 2183-2196 ( doi : 10.1093 / nar / 22.12 .2183 , PMC 523672 (free full text), PMID 7518580 ).