Uridine

from Wikipedia, the free encyclopedia
Structural formula
Structural formula of uridine
General
Surname Uridine
other names
  • U (short code)
  • 1 - [(2R, 3R, 4S, 5R) -3,4-dihydroxy-5- (hydroxymethyl) oxolan-2-yl] -2,4-dioxo-3 H -pyrimidine
  • Uracil riboside
  • Uracil-1- β - D -ribofuranoside
  • 1- β - D -ribofuranosyluracil
  • 1- β - D -ribofuranosyl- (1 H , 3 H ) -pyrimidine-2,4-dione
  • URIDINE ( INCI )
Molecular formula C 9 H 12 N 2 O 6
Brief description

colorless, prismatic needles

External identifiers / databases
CAS number 58-96-8
EC number 200-407-5
ECHA InfoCard 100,000,370
PubChem 6029
ChemSpider 5807
DrugBank DB02745
Wikidata Q422573
properties
Molar mass 244.20 g mol −1
Physical state

firmly

Melting point

165-168 ° C

solubility

soluble in water, insoluble in diethyl ether

safety instructions
GHS labeling of hazardous substances
no GHS pictograms
H and P phrases H: no H-phrases
P: no P-phrases
Toxicological data

4335 mg m −3 ( LD 50 ,  mouse ,  ip )

As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Uridine ( U ) is a nucleoside and consists of the nucleobase uracil and the sugar β- D- ribose .

Uridine is part of ribonucleic acid (RNA) and forms a base pair there with adenosine .

Structural formula of an AU base pair

In the deoxyribonucleic acid (DNA), however, only deoxythymidine occurs (see genetic code ). Another analogue with deoxyribose is deoxyuridine .

Related links

Individual evidence

  1. ↑ Entry on URIDINE in the CosIng database of the EU Commission, accessed on May 7, 2020.
  2. ↑ a b c Entry on uridine. In: Römpp Online . Georg Thieme Verlag, accessed on October 26, 2014.
  3. ↑ Data sheet Uridine, ≥99% from Sigma-Aldrich , accessed on February 24, 2013 ( PDF ).
  4. ↑ Entry on uridine in the ChemIDplus database of the United States National Library of Medicine (NLM) .

Web links

Wikibooks: Biochemistry and Pathobiochemistry: Pyrimidine Metabolism  - Learning and Teaching Materials
Commons : Uridine  - collection of pictures, videos and audio files
Commons : Uridine derivatives  - collection of pictures, videos and audio files
  • Entry for Uridine in the Human Metabolome Database (HMDB) , accessed October 12, 2013.
  • Modification Summary of Uridine in the Modomics database, accessed January 14, 2014.