5-methoxyuridine
Structural formula | ||||||||||||||||
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General | ||||||||||||||||
Surname | 5-methoxyuridine | |||||||||||||||
other names |
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Molecular formula | C 10 H 14 N 2 O 7 | |||||||||||||||
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properties | ||||||||||||||||
Molar mass | 274.23 g mol −1 | |||||||||||||||
Physical state |
firmly |
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safety instructions | ||||||||||||||||
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
5-methoxyuridine (mo 5 U) is a rare nucleoside and occurs in the tRNA . It consists of β- D- ribofuranose (sugar) and the nucleic base 5-methoxyuracil . It is a derivative of uridine .
literature
- K. Murao, H. Ishikura, M. Albani, H. Kersten: On the biosynthesis of 5-methoxyuridine and uridine-5-oxyacetic acid in specific procaryotic transfer RNAs , Nucleic Acids Research , 1978 , 5 (4), p. 1273 -1281 ( PMC 342075 (free full text); PMID 418384 ).
- George I. Birnbaum, Wayne JP Blonski, Frank E. Hruska: Structure and conformation of the anticodon nucleoside 5-methoxyuridine in the solid state and in solution . In: Canadian Journal of Chemistry . 61 (10), 1983, pp. 2299-2304, doi : 10.1139 / v83-399 .
- George I. Birnbaum, Wayne JP Blonski, Frank E. Hruska: Structure and conformation of the anticodon nucleoside 5-methoxyuridine in the solid state and in solution . In: Canadian Journal of Chemistry . 61 (12), 1983, p. 2829, doi : 10.1139 / v83-488 .
Individual evidence
- ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
- ↑ Patrick A. Limbach, Pamela F. Crain, James A. McCloskey: Summary: the modified nucleosides of RNA , Nucleic Acids Research , 1994 , 22 (12), pp. 2183-2196 ( doi: 10.1093 / nar / 22.12.2183 ; PMC 523672 (free full text); PMID 7518580 ).
Web links
- Modification Summary of 5-Methoxyuridine in the Modomics database, accessed January 13, 2014.