Orotidine

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Structural formula
Structural formula of orotidine
General
Surname Orotidine
other names
  • O (short code)
  • 1- β - D -ribofuranosyl- (1 H , 3 H ) -pyrimidine-2,4-dione-6-carboxylic acid
  • 1 - [(2 R , 3 R , 4 S , 5 R ) -3,4-dihydroxy-5- (hydroxymethyl) oxolan-2-yl] -2,4-dioxo-3 H -pyrimidine-6-carboxylic acid
Molecular formula C 10 H 12 N 2 O 8
External identifiers / databases
CAS number 314-50-1
PubChem 92751
ChemSpider 83729
Wikidata Q10859719
properties
Molar mass 288.21 g mol −1
Physical state

firmly

safety instructions
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Orotidine (O) is a rare nucleoside and is structurally derived from uridine . It consists of β- D- ribofuranose (sugar) and orotic acid . It was first isolated from the Neurospora fungus in 1951 . It forms an intermediate stage in the biosynthesis of uridine monophosphate (UMP).

Individual evidence

  1. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
  2. ^ A. Michael Michelson, William Drell, Herschel K. Mitchell : A new ribose nucleoside from Neurospora: "orotidine" , Proc Natl Acad Sci USA , 1951 , 37  (7), pp. 396-399 ( doi : 10.1073 / pnas. 37.7.396 ; PMC 1063384 (free full text); PMID 14853953 ).

Web links

Wikibooks: Biochemistry and Pathobiochemistry: Pyrimidine Metabolism  - Learning and Teaching Materials
  • Entry for Orotidine in the Human Metabolome Database (HMDB) , accessed October 12, 2013.