Ribothymidine
Structural formula | ||||||||||||||||
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General | ||||||||||||||||
Surname | Ribothymidine | |||||||||||||||
other names |
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Molecular formula | C 10 H 14 N 2 O 6 | |||||||||||||||
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properties | ||||||||||||||||
Molar mass | 258.23 g mol −1 | |||||||||||||||
Physical state |
firmly |
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Melting point |
183-184 ° C |
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safety instructions | ||||||||||||||||
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Ribothymidine (often also 5-methyluridine ) is a rare nucleoside and occurs in tRNA and rRNA . It consists of β- D- ribofuranose (sugar) and the nucleobase thymine . The analogue with deoxyribose that occurs as standard in DNA is deoxythymidine , which is often referred to simply as thymidine .
Ribothymidine sits in the TΨC loop of tRNA.
Individual evidence
- ↑ a b c data sheet 5-methyluridine from Sigma-Aldrich , accessed on March 11, 2011 ( PDF ).
- ↑ Patrick A. Limbach, Pamela F. Crain, James A. McCloskey: "Summary: the modified nucleosides of RNA", Nucleic Acids Research , 1994 , 22 (12), pp. 2183-2196 ( doi : 10.1093 / nar / 22.12 .2183 , PMC 523672 (free full text), PMID 7518580 ).
- ^ Robert W. Holley , Jean Apgar, George A. Everett, James T. Madison, Mark Marquisee, Susan H. Merrill, John Robert Penswick, Ada Zamir: "Structure of a Ribonucleic Acid", Science , 1965 , 147 , pp. 1462-1465 ( doi : 10.1126 / science.147.3664.1462 ).
Web links
- Entry for ribothymidines in the Human Metabolome Database (HMDB) , accessed September 24, 2013.
- Modification Summary of 5-methyluridine in the Modomics database, accessed January 14, 2014.