5-aza-7-deazaguanine

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Structural formula
Structure of 5-aza-7-deazaguanine
General
Surname 5-aza-7-deazaguanine
other names

2-Aminoimidazo [1,2- a ] [1,3,5] triazin-4 (1 H ) -one

Molecular formula C 5 H 5 N 5 O
External identifiers / databases
CAS number 67410-64-4
PubChem 135600909
ChemSpider 10205066
Wikidata Q61876713
properties
Molar mass 151.13 g mol −1
Physical state

firmly

safety instructions
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

5-Aza-7-deazaguanine is a heterocyclic organic compound with a modified purine backbone. It is a derivative of the nucleobase guanine and occurs as part of the Hachimoji DNA .

Extraction and presentation

5-Aza-7-deazaguanine can be obtained from cyanuric chloride in a multi-stage reaction .

Individual evidence

  1. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
  2. ↑ Shuichi Hoshika, Nicole A. Leal and a .: Hachimoji DNA and RNA: A genetic system with eight building blocks. In: Science . 363, 2019, pp. 884–887, doi : 10.1126 / science.aat0971 .
  3. ^ CK Chu: Recent Advances in Nucleosides: Chemistry and Chemotherapy . Elsevier, 2002, ISBN 978-0-08-054036-8 , pp. 524 ( limited preview in Google Book search).