Achlorhydria
| Classification according to ICD-10 | |
|---|---|
| K31.8 | Other specified diseases of the stomach and duodenum achlorhydria |
| ICD-10 online (WHO version 2019) | |
As Achlorhydria a lack of will stomach acid in gastric juice called.
In the case of absolute achlorhydria , acid production cannot be provoked by the administration of pentagastrin (= pentagastrin-refractory anacidity); in the case of relative or chemical achlorhydria , this only appears to be absent, e.g. B. pyloric insufficiency with their reflux of alkaline small intestine contents .
Absolute achlorhydria can occur in type A gastritis (corpus gastritis, autoimmune gastritis ), as this leads to a decrease in the parietal cells of the gastric mucosa . Removal of the stomach or vagotomy also leads to achlorhydria. It is also an early symptom of pernicious anemia and, in addition to watery diarrhea and hypokalemia, also one of the symptoms of WDHA syndrome . A constant lack of hydrochloric acid is also detected with a fractional examination of the stomach contents .
Since gastric acid promotes the absorption of iron , achlorhydria leads to malabsorption and thus to an iron deficiency (see iron metabolism ).
