Acid Violet 17

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Structural formula
Structure of CI Acid Violet 17
General
Surname Acid Violet 17
other names
  • Sodium ( E ) -3 - {[(4 - {[4- (diethylamino) phenyl] {4- [ethyl (3-sulfonatobenzyl) amino] phenyl} methylene} cyclohexa-2,5-dienylidene) (ethyl) ammonio ] methyl} benzenesulfonate ( IUPAC )
  • CI 42650
  • Coomassie Violet R200
Molecular formula C 41 H 44 N 3 NaO 6 S 2
Brief description

dark purple solid

External identifiers / databases
CAS number 4129-84-4
EC number 223-942-6
ECHA InfoCard 100,021,766
PubChem 92205
Wikidata Q1129730
properties
Molar mass 761.9 g mol −1
Physical state

firmly

safety instructions
GHS labeling of hazardous substances
no GHS pictograms
H and P phrases H: no H-phrases
P: no P-phrases
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

CI Acid Violet 17 is an acid dye from the group of triphenylmethane dyes .

use

Acid Violet 17 is used in different areas of application, for example in the textile industry, biochemistry and medicine.

In biochemistry, the dye is used to stain proteins in polyacrylamide gel electrophoresis .

The ability to specifically bind to certain proteins is also used in medicine. In order to specifically mark tissues and to make them distinguishable from one another for tissue removal (e.g. in cataract, cornea or retinal surgery), triphenylmethane dyes such as Coomassie brilliant blue , bromophenol blue , patent blue V or crystal violet have been used in surgery since the turn of the millennium . Tumor diagnoses or the treatment of skin fungi (fungicidal effect of crystal violet) have also been described.

Surname

The original trade name of the product developed as a wool dye was Coomassie brilliant violet. The name comes from the African city of Kumasi in Ghana and was chosen to commemorate the British occupation of the then Ashanti capital Coomassie - now Kumasi - in 1896. Coomassie was originally a registered trademark of Imperial Chemical Industries .

literature

  • MC Morales, V. Freire, A. Asumendi, J. Araiz, I. Herrera, G. Castiella, I. Corcóstegui, G. Corcóstegui: Comparative effects of six intraocular vital dyes on retinal pigment epithelial cells. In: Investigative ophthalmology & visual science. Volume 51, Number 11, November 2010, pp. 6018-6029, doi : 10.1167 / iovs.09-4916 . PMID 20554611 .
  • EB Rodrigues, M. Maia, CH Meyer, FM Penha, E. Dib, ME Farah: Vital dyes for chromovitrectomy. In: Current opinion in ophthalmology. Volume 18, Number 3, May 2007, pp. 179-187, doi : 10.1097 / ICU.0b013e32811080b5 . PMID 17435423 .
  • ME Farah, M. Maia, EB Rodrigues: Dyes in ocular surgery: principles for use in chromovitrectomy. In: American journal of ophthalmology. Volume 148, Number 3, September 2009, pp. 332-340, doi : 10.1016 / j.ajo.2009.04.003 . PMID 19477708 .
  • S. Mennel, CH Meyer, JC Schmidt, S. Kaempf, G. Thumann: Trityl dyes patent blue V and brilliant blue G - clinical relevance and in vitro analysis of the function of the outer blood-retinal barrier. In: Developments in ophthalmology. Volume 42, 2008, pp. 101-114, doi : 10.1159 / 000138988 . PMID 18535384 .
  • MG de Oliveira, AC Chaves, F. Visioli, EU Rojas, SP Moure, J. Romanini, JE Mariath, PV Rados, M. Sant'ana Filho: Peripheral clear cell variant of calcifying epithelial odontogenic tumor affecting 2 sites: report of a case. In: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. Volume 107, Number 3, March 2009, pp. 407-411, doi : 10.1016 / j.tripleo.2008.11.004 . PMID 19157927 .
  • B. Bonnekoh, A. Wevers, F. Jugert, H. Merk, G. Mahrle: Colorimetric growth assay for epidermal cell cultures by their crystal violet binding capacity. In: Archives of Dermatological Research . Volume 281, Number 7, 1989, pp. 487-490, PMID 2482013 .

Individual evidence

  1. ↑ a b c Data sheet Coomassie Violet R200 from Sigma-Aldrich , accessed on July 11, 2019 ( PDF ).