Actinidain
| Actinidain ( Actinidia chinensis ) | ||
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| Ribbon model of the enzyme from Actinidia chinensis , according to PDB 1AEC | ||
| Mass / length primary structure | 254 amino acids | |
| Precursor | (380 aa) | |
| Identifier | ||
| External IDs |
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| Enzyme classification | ||
| EC, category | 3.4.22.14 , cysteine protease | |
| MEROPS | C01.007 | |
| Response type | Peptide cleavage | |
| Substrate | protein | |
| Products | smaller proteins | |
| Occurrence | ||
| Parent taxon | Creature | |
Actinidain is an enzyme found in the kiwi fruit that catalyzes the breakdown of proteins . It causes an allergic reaction in some people and has been identified as the main allergen in kiwi fruit. Technically, actinidain is ideal for breaking down collagen and separating cell types in mixed meat tissues.
Since actinidain contains cysteine in the active center , it is a cysteine protease . Close relatives of the enzyme are found in all ray pen fruits and in the fruits of the cedar tree . Other relatives can be found in pineapple , mango and papaya ( papain ).
Individual evidence
- ↑ Interpro entry .
- ↑ E. Pastorello et al .: Identification of actinidin as the major allergen of kiwi fruit , Journal of Allergy and Clinical Immunology , 101 (4), pp. 531-537, PMID 9564807 .
- ↑ Mostafaie et al .: Kiwifruit actinidin: a proper new collagenase for isolation of cells from different tissues. Appl. Biochem. Biotechnol. 144: 123-131 (2008), PMID 18456944 .
- ↑ MEROPS entry family C01A .