Alexander Alexejewitsch Makarov

Alexander Alexejewitsch Makarow ( Russian Александр Алексеевич Макаров ; born June 2, 1966 in Irkutsk ) is a Russian physicist . He is considered to be the inventor of the orbitrap .

Life

Makarov studied at the Moscow Institute of Technical Physics ( MEPhI ). After receiving his doctorate, he worked at the Prokhorov General Physics Institute of the Russian Academy of Sciences (GPI RAS) from 1992 . In 1996 he moved to the small high-tech company HD Technologies in Manchester . Work on a working prototype of a high-resolution mass spectrometer , the Orbitrap , was published by him in 2000. Technical advancements led to the first commercial device in 2005, which was marketed by Thermo Fisher Scientific as a coupling Linear trap / Orbitrap. The Orbitrap is now available with a linear trap (“LTQ Orbitrap”), quadrupole (“Q Exactive”) or coupled directly to an ion source (“Exactive”). Alexander Makarow has lived in Bremen with his family since 2006 and is Director of Research in Life Sciences Mass Spectrometry at Thermo Fisher Scientific.

Honors

Heinrich Emanuel Merck Prize (2007)
Gold Award of the Russian Society for Mass Spectrometry (2007)
John B. Fenn Award for a Distinguished Contribution in Mass Spectrometry from the American Society for Mass Spectrometry (2008)
Curt Brunnée Research Award (2009)
Science and Technology Award from the Human Proteome Organization (2011)
Thomson Medalist of the International Mass Spectrometry Foundation (2012)
Member of the Royal Society (2020)

Web links

Alexander Makarov: The Inventor , engl.
Purdue University Orbitrap Page , engl.

literature

Keith A. Nier, Alfred L. Yergey, P. Jane Gale: The Encyclopedia of Mass Spectrometry: Volume 9: Historical Perspectives , Elsevier, 2015.

Individual evidence

↑ A. Makarov: Electrostatic Axially harmonic orbital trapping: A high-performance technique of mass analysis . In: Analytical Chemistry . 72, No. 6, 2000, pp. 1156-62. doi : 10.1021 / ac991131p .
^ A. Makarov, E. Denisov, A. Kholomeev, W. Balschun, O. Lange, K. Strupat, S. Horning: Performance evaluation of a hybrid linear ion trap / orbitrap mass spectrometer . In: Analytical Chemistry . 78, No. 7, 2006, pp. 2113-20. doi : 10.1021 / ac0518811 .

personal data
SURNAME	Makarov, Alexander Alexejewitsch
ALTERNATIVE NAMES	Makarov, Alexander Alexeyevich; Макаров, Александр Алексеевич (Russian)
BRIEF DESCRIPTION	Russian physicist
DATE OF BIRTH	June 2, 1966
PLACE OF BIRTH	Irkutsk

[Mak1-1] A. Makarov: Electrostatic Axially harmonic orbital trapping: A high-performance technique of mass analysis . In: Analytical Chemistry . 72, No. 6, 2000, pp. 1156-62. doi : 10.1021 / ac991131p .

[Mak2-2] A. Makarov, E. Denisov, A. Kholomeev, W. Balschun, O. Lange, K. Strupat, S. Horning: Performance evaluation of a hybrid linear ion trap / orbitrap mass spectrometer . In: Analytical Chemistry . 78, No. 7, 2006, pp. 2113-20. doi : 10.1021 / ac0518811 .