Alpha-1,3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase B
Alpha-1,3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase B | ||
---|---|---|
other names |
|
|
Cofactor | Bivalent metal cation | |
Identifier | ||
Gene name (s) | MGAT4B GNT-IVB | |
External IDs | ||
Orthologue | ||
human | House mouse | |
Entrez | 11282 | 103534 |
Ensemble | ENSG00000161013 | ENSMUSG00000036620 |
UniProt | Q9UQ53 | Q812F8 |
Refseq (mRNA) | NM_014275 | NM_145926 |
Refseq (protein) | NP_055090 | NP_666038 |
Gene locus | Chr 5: 179.8 - 179.81 Mb | Chr 11: 50.21 - 50.24 Mb |
PubMed search | 11282 |
103534
|
The alpha-1,3-mannosyl glycoprotein 4-beta-N-acetylglucosaminyltransferase B is an enzyme , more precisely a glycosyltransferase , which is involved in the transfer of N-acetylglucosamine to mannose residues of N-linked glycan . It analyzes the formation of N-acetylglucosamine-beta 1-4 branches on the N-acetylglucosamine-beta-1-2-manalpha-1-3 arm of the core structure of N-linked glycans. It is therefore essential for the formation of three- or four-way branched N-linked sugar chains.