Alternariol
Structural formula | |||||||||||||||||||
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AOH (top), AME (bottom) | |||||||||||||||||||
General | |||||||||||||||||||
Surname | Alternariol | ||||||||||||||||||
other names |
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Molecular formula |
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properties | |||||||||||||||||||
Molar mass | |||||||||||||||||||
Physical state |
firmly |
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safety instructions | |||||||||||||||||||
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Alternariol (abbreviation: AOH ) and its monomethyl ether (abbreviation: AME ) are mycotoxins that are formed by molds of the genus Alternaria , especially Alternaria alternata . Their biosynthesis takes place via a polyketide pathway. Because of the ubiquitous distribution of Alternaria spp. their toxins occur in many foods. They can be found in vegetables and fruits such as tomatoes, potatoes, mandarins, melons, grapes, apples, raspberries or strawberries, in cereals such as millet, wheat or rye, in olives or in nuts. While the acute toxicity of AOH and AME is low, they show significant mutagenic activity in vitro . They have been linked to the development of esophageal cancer .
literature
- NH Schebb: In vitro metabolism of the mycotoxins alternariol and alternariol monomethyl ether (PDF; 1.8 MB). Diploma thesis, 2005.
Individual evidence
- ↑ a b Datasheet Alternariol from Alternaria sp. at Sigma-Aldrich , accessed on March 20, 2011 ( PDF ).