Andres Jäschke

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Year 2012

Andres Jäschke (born August 31, 1962 in Halle ) is a German chemist and professor of pharmaceutical and bio-organic chemistry at Heidelberg University . There he heads the chemistry department at the Institute for Pharmacy and Molecular Biotechnology . From 2012 to 2016 Jäschke was Dean of the Faculty of Biosciences.

He is married and has two children.

Career

Andres Jäschke studied chemistry at the Humboldt University in Berlin , then worked as a research assistant in the chemistry department, where he received his doctorate in 1993. rer. nat. with “summa cum laude”. Until 1995 he worked as a postdoc at the Department of Biology at the Massachusetts Institute of Technology , then until 2002 as a research assistant / working group leader at the Institute for Biochemistry at the Free University of Berlin. Jäschke has held the Chair of Pharmaceutical and Bioorganic Chemistry at the Ruprecht-Karls-Universität Heidelberg since 2002.

Scholarships and Scientific Prizes

From 1993 to 1995 he received a postdoctoral fellowship from the German Academic Exchange Service. In 1999 he was a prize winner in the BMBF's “BIOFUTURE” competition, and two years later he received the Helmut Bredereck grant for bio-organic chemistry. In 2010 he was awarded the “Distinguished lecturer medal” from the Italian Chemical Society .

Membership in scientific societies

Current scientific research areas

  • Chemical biology of nucleic acids
  • RNA and DNA catalysis
  • Molecular Switches
  • Hybrid catalysts made from biopolymers and transition metal compounds
  • RNA as a drug target / New biological functions of RNA
  • Bioorthogonal modification and labeling reactions

Publications (selection)

  • Jäschke, A .: Oligonucleotide-Polyethylene Glycol Conjugates. Synthesis, characterization and applications . Humboldt University (dissertation), Berlin 1993.
  • Burckhard Seelig, Andres Jäschke: A small catalytic RNA motif with Diels-Alderase activity . In: Chemistry & Biology . tape 6 , no. 3 , 1999, p. 167-176 , doi : 10.1016 / S1074-5521 (99) 89008-5 .
  • Alexander Serganov, Sonja Keiper, Lucy Malinina, Valentina Tereshko, Eugene Skripkin, Claudia Höbartner, Anna Polonskaia, Anh Tuân Phan, Richard Wombacher, Ronald Micura, Zbigniew Dauter, Andres Jäschke, Dinshaw J. Patel: Structural basis for Diels-Alder ribozyme- catalyzed carbon-carbon bond formation . In: Nature Structural & Molecular Biology . tape 12 , no. 3 , February 20, 2005, p. 218-224 , doi : 10.1038 / nsmb906 .
  • Pierre Fournier, Roberto Fiammengo, Andres Jäschke: Allylic Amination by a DNA-Diene-Iridium (I) Hybrid Catalyst . In: Angewandte Chemie International Edition . tape 48 , no. 24 , June 2, 2009, ISSN  1521-3773 , p. 4426-4429 , doi : 10.1002 / anie.200900713 .

Web links

personal data
SURNAME Jaschke, Andres
BRIEF DESCRIPTION German chemist and professor at Heidelberg University
DATE OF BIRTH August 31, 1962
PLACE OF BIRTH Hall