Asimicin

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Structural formula
Structure of asimicin
General
Surname Asimicin
other names
  • (+) - asimicin
  • Squamocin H
Molecular formula C 37 H 66 O 7
External identifiers / databases
CAS number 102989-24-2
PubChem 114749
Wikidata Q730429
properties
Molar mass 622.93 g mol −1
safety instructions
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Asimicin is a naturally occurring compound from the group of Anno Nine (mono- and di tetrahydrofuran fatty -γ- lactone ). The compound with the molecular formula C 37 H 66 O 7 and the molar mass 622.93 g / mol occurs in the Indian banana Asimina triloba and in the cinnamon apple Annona squamosa .

The cytotoxin has a cancer-inhibiting effect in mice by disrupting the transport of electrons in the mitochondria of the rapidly growing cancer cells. There it acts as an inhibitor on complex I of the respiratory chain. Chemically, it is a fatty acid lactone that belongs to the class of acetogenins .

Individual evidence

  1. This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
  2. Entry on Annonine. In: Römpp Online . Georg Thieme Verlag, accessed on December 4, 2011.
  3. Lexicon of Biology: Asimicin on Wissenschaft-online.de