CCL14
CCL14 | ||
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other names |
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Properties of human protein | ||
Mass / length primary structure | 93 amino acids, 10,678 Da (isoform 1)
109 amino acids, 12,297 Da (isoform 2) |
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Isoforms | 2 | |
Identifier | ||
Gene names | CCL14 SCYA14, NCC2, HCC-3, CKB1, MCIF, SY14 | |
External IDs | ||
Orthologue (human) | ||
Entrez | 6358 | |
Ensemble | ENSG00000276409 | |
UniProt | Q16627 | |
Refseq (mRNA) | NM_032962 | |
Refseq (protein) | NP_116738 | |
Gene locus | Chr 17: 35.98 - 35.99 Mb | |
PubMed search |
6358
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CCL14 ( English CC chemokine ligand 14 , synonym HCC-1 ) is a cytokine from the family of CC chemokines .
properties
CCL14 is a preprotein and is cleaved into an active form of 76 amino acids. The active form is involved in inflammatory processes. CCL14 has a high degree of homology to CCL3 and CCL4 . It activates monocytes . CCL14 is produced in the spleen , bone marrow , liver , muscles and intestines .
Individual evidence
- ↑ Schulz-Knappe et al., HCC-1, a novel chemokine from human plasma. J. Exp. Med., 1996, 183: 295-299.