CCL3
CCL3 | ||
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according to PDB 1B50 | ||
other names |
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Existing structural data : 1B50 , 1B53 , 2X69 , 2X6G , 3FPU , 3H44 |
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Properties of human protein | ||
Mass / length primary structure | 92 amino acids, 10085 Da | |
Secondary to quaternary structure | Monomer | |
Identifier | ||
External IDs |
CCL3 (synonym MIP1α) is a cytokine from the family of CC chemokines .
properties
CCL3 is involved in inflammatory processes. It binds polymorphonuclear leukocytes by binding the receptors CCR1 , CCR4 and CCR5 . CCL3 is involved in the pathogenesis of chromoblastomycosis and the defense against infections with HIV- 1.
Individual evidence
- ↑ Ennan Guan, Jinhai Wang, Michael A. Norcross: Identification of human macrophage inflammatory proteins 1alpha and 1beta as a native secreted heterodimer . In: The Journal of biological chemistry . 276, No. 15, United States, April 2001, ISSN 0021-9258 , pp. 12404-9. doi : 10.1074 / jbc.M006327200 . PMID 11278300 .