CCL15

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CCL15
other names
  • Chemokine (CC Motif) ligand 15
  • Macrophage Inflammatory Protein 5
  • Chemokine CC-2
  • MIP-1 delta
  • SCYA15
  • NCC3
  • Small Inducible Cytokine Subfamily A (Cys-Cys), Member 15
  • Leukotactin 1
  • MRP-2B
  • HCC-2
  • LKN-1
  • MIP-5
  • HMRP-2B
  • SY15

Available structural data : 2HCC

Properties of human protein
Mass / length primary structure 113 amino acids, 12248 Da
Identifier
External IDs

CCL15 ( English CC chemokine ligand 15 ) is a cytokine belonging to the family of the C-C chemokines .

properties

CCL15 is involved in inflammatory processes. It is chemotactic for and activates various immune cells , including neutrophils , monocytes, and T cells . CCL15 is produced in the liver , intestines, and leukocytes and macrophages of the lungs . CCL15 binds to CCR1 and CCR3 .

Individual evidence

  1. ↑ Pardigol et al. HCC-2, a human chemokine: gene structure, expression pattern, and biological activity. Proc. Nat. Acad. Sci. 95: 6308-6313,1998.
  2. ↑ Youn et al. Molecular cloning of leukotactin-1: a novel human beta-chemokine, a chemoattractant for neutrophils, monocytes, and lymphocytes, and a potent agonist at CC chemokine receptors 1 and 3. J. Immun. 159: 5201-5205, 1997.
  3. ↑ Coulin et al. Characterization of macrophage inflammatory protein-5 / human CC cytokine-2, a member of the macrophage-inflammatory-protein family of chemokines. Europ. J. Biochem. 248: 507-515, 1997.