Cannabigerol

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Structural formula
Structural formula of cannabigerol
General
Surname Cannabigerol
other names
  • CBG
  • ( E ) -CBG
  • CBG-C5
  • ( E ) -2- (3,7-dimethylocta-2,6-dienyl) -5-pentylbenzene-1,3-diol ( IUPAC )
Molecular formula C 21 H 32 O 2
External identifiers / databases
CAS number
  • 2808-33-5
  • 25654-31-3
PubChem 5315659
ChemSpider 4474921
Wikidata Q412122
Drug information
Drug class

Cannabinoids

properties
Molar mass 316.48 g mol −1
safety instructions
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Cannabigerol ( CBG ) is a non-psychoactive cannabinoid found in several types of cannabis . It binds to the cannabinoid receptor CB 1 with millimolar affinity . The concentration of CBG in cannabis indica is higher than in other cannabis species.

Cannabigerol is not subject to the BtMG in Germany .

Possible medical use

CBG moderately lowers intraocular pressure in cats.

An antibiotic effect against multi-resistant Staphylococcus aureus ( MRSA ) could be demonstrated in vivo in mice.

Individual evidence

  1. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
  2. ↑ K. Hayakawa, K. Mishima, M. Fujiwara: Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke. In: Pharmaceuticals. Volume 3, number 7, July 2010, pp. 2197-2212, doi : 10.3390 / ph3072197 , PMID 27713349 , PMC 4036658 (free full text).
  3. ^ AJ Hill, CM Williams, BJ Whalley, GJ Stephens: Phytocannabinoids as novel therapeutic agents in CNS disorders. In: Pharmacology & therapeutics. Volume 133, number 1, January 2012, pp. 79-97, doi : 10.1016 / j.pharmthera.2011.09.002 , PMID 21924288 .
  4. ↑ Brenda K. Colasanti: A Comparison of the Ocular and Central Effects of Δ9-Tetrahydrocannabinol and Cannabigerol . In: Journal of Ocular Pharmacology and Therapeutics . tape 6 , no. 4 , 1990, pp. 259-269 , doi : 10.1089 / jop.1990.6.259 .
  5. ↑ Maya A. Farha, Omar M. El-Halfawy, Robert T. Gale, Craig R. MacNair, Lindsey A. Carfrae: Uncovering the Hidden Antibiotic Potential of Cannabis . In: ACS Infectious Diseases . tape 6 , no. 3 , March 13, 2020, ISSN  2373-8227 , p. 338–346 , doi : 10.1021 / acsinfecdis.9b00419 ( acs.org [accessed May 6, 2020]).