Cefaclor
Structural formula | ||||||||||||||||||||||
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General | ||||||||||||||||||||||
Non-proprietary name | Cefaclor | |||||||||||||||||||||
other names |
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Molecular formula | C 15 H 14 ClN 3 O 4 S | |||||||||||||||||||||
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properties | ||||||||||||||||||||||
Molar mass | 367.81 g mol −1 | |||||||||||||||||||||
solubility |
soluble in hydrochloric acid (1 mol·l −1 ) |
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safety instructions | ||||||||||||||||||||||
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Cefaclor is an antibiotic . It belongs to the second generation of the cephalosporins . Cefaclor is administered orally and can be used against gram-positive and gram-negative bacteria.
Side effects
- Often allergic reactions, allergic neutropenia, phlebitis, gastrointestinal complaints
- Occasionally increased transaminases and alkaline phosphatase, changes in the blood count, dizziness, hypertension
- Rarely, pesudomembranous colitis
- Very rarely lymphocytosis, leukopenia, hepatitis, cholestasis
Contraindications
Cefaclor is contraindicated in cephalosporin allergy. Because of the risk of cross allergy, the drug should be used with caution in the case of penicillin allergy.
Web links
- Entry on Cefaclor in Pharmawiki
Individual evidence
- ↑ a b c data sheet Cefaclor from Sigma-Aldrich , accessed on December 30, 2011 ( PDF ).
- ^ Marianne Abele-Horn: Antimicrobial Therapy. Decision support for the treatment and prophylaxis of infectious diseases. With the collaboration of Werner Heinz, Hartwig Klinker, Johann Schurz and August Stich, 2nd, revised and expanded edition. Peter Wiehl, Marburg 2009, ISBN 978-3-927219-14-4 , p. 339.