Cianopramine

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Structural formula
Structure of cianopramine
General
Non-proprietary name Cianopramine
other names
  • 11- (3-Dimethylaminopropyl) -5,6-dihydrobenzo [ b ] [1] benzazepine-9-carbonitrile ( IUPAC )
  • 3-cyanoimipramine
  • Ro11-2465
Molecular formula C 20 H 23 N 3
External identifiers / databases
CAS number 66834-24-0
PubChem 48126
Wikidata Q1091386
Drug information
ATC code

N06 AA02

Drug class

Tricyclic antidepressant

properties
Molar mass 305.42 g mol −1
safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Cianopramine ( INN ) is an organic chemical compound belonging to the azepine group . It is used as a drug belonging to the group of tricyclic antidepressants .

Cianopramine is related to imipramine and like this acts as a serotonin reuptake inhibitor and as a weak antagonist at the 5-HT receptor . In contrast to the antidepressants from the amitriptyline group, it has a less pronounced anticholinergic effect.

Individual evidence

  1. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
  2. ↑ M. Kenny, TJ Lenehan, R. Lambe, A. Darragh, I. Brick, LM Omer: Effects of a single oral dose of 3-cyano-imipramine on serotonin uptake and content of platelets in healthy volunteers. In: Psychopharmacology (Berlin). (79/1983), pp. 304-307. PMID 6407042 .
  3. ↑ L. Pawłowski, H. Kwiatek, Z. Górka: Is Ro 11-2465 (cyan-imipramine) an antagonist of postsynaptic serotonin receptors? In: Journal of Neural Transmission. (52/1981), pp. 61-72. PMID 7288439 .
  4. ↑ L. Hormazabal, LM Omer, S. Ismail: Cianopramine and amitriptyline in the treatment of depressed patients - a placebo-controlled study. In: Psychopharmacology (Berl). 86 (1-2), 1985, pp. 205-208. PMID 3927356 .