David A. Sinclair

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David Andrew Sinclair AO (born June 26, 1969 in Sydney , Australia ) is an Australian biologist and professor of genetics who specializes in the study of aging processes .

Life

Sinclair attended St. Ives High School in Sydney. He received his PhD Summa cum laude from the University of New South Wales (UNSW) in Biochemistry and Molecular Genetics. He has been Director of the Paul F. Glenn Laboratories for the Elucidation of Biological Mechanisms of Aging at Harvard Medical School (HMS) in Cambridge since 2005 . He is professor at the Lowy Cancer Center in the pharmacology department at UNSW and since 1999 full professor in the genetics department at HMS.

Sinclair is married and has three children.

job

Sinclair deals with the coenzyme nicotinamide adenine dinucleotide (NAD). As a versatile information transport mechanism, it moves protons and electrons from one place to another within the cell. By increasing the NAD, the energy metabolism is improved. Sinclair suspects that the amount of NAD plays an important role in aging.

Lectures

At the TEDx Sydney in 2008 he gave the lecture "A Cure for Aging?" and in October 2009 at TEDMED the lecture: "Can a pill a day help keep aging away?".

Books

  • The end of aging. The revolutionary medicine of tomorrow . Together with Matthew. D. LaPlante. Translated by Sebastian Vogel. DuMont Buchverlag , Cologne 2019, ISBN 978-3832181048 .

Awards

  • 1995: The Australian Commonwealth Prize
  • Nathan Shock Award
  • MERIT Award from the National Institutes of Health
  • Merck Prize
  • 2004: Genzyme Outstanding Achievement in Biomedical Science Award
  • 2006: Bio-Innovator Award
  • 2006: Bright Sparks Award for top scientists under 45 from Cosmos magazine

Companies

Sinclair founded five biotechnology companies: To fight diseases (Sirtris, NASDAQ : SIRT), reproductive medicine (OvaScience, NASDAQ: OVAS), to fight type 2 diabetes (Cohbar), develop vaccines against malaria, chlamydial infection, Tuberculosis, high blood pressure and cancer (Genocea), and against aging (MetroBiotech).

In 2008, Sinclair sold Sirtris Pharmaceuticals to pharmaceutical company GlaxoSmithKline for $ 720 million .

Trivia

Sinclair's research was thematized in the documentary "To Age or Not to Age" (2010).

Web links

Individual evidence

  1. ↑ Judyth Piazza chats with Dr. David A. Sinclair and Dr. Jamie McManus about RESVERATROL , the Sop, November 18, 2008
  2. ^ The Paul F. Glenn Laboratories for the Biological Mechanisms of Aging
  3. ^ The Sinclair Lab
  4. ↑ Researchers make hope for eternal youth , Die Welt, December 20, 2013
  5. ↑ A Cure for Aging ?: David Sinclair at TEDxSydney on Youtube
  6. ^ TEDMED Speaker: David Sinclair
  7. ↑ Heather Jacobs: The tablet of youth , Australia Unlimited, April 19, 2013
  8. ↑ http://genetics.med.harvard.edu/sinclair/people-sinclair.php
  9. ^ Science Café with David A. Sinclair
  10. ↑ Kate Holdsworth: Cosmos Bright Sparks: Australia's top 10 young minds ( memento of the original from December 26, 2013 in the Internet Archive ) Info: The archive link was automatically inserted and not yet checked. Please check the original and archive link according to the instructions and then remove this notice. , Cosmos, July 26, 2006 @1@ 2Template: Webachiv / IABot / www.cosmosmagazine.com
  11. ^ Wade Roush: GlaxoSmithKline Scoops Up Sirtris , xconomy, August 22, 2008
personal data
SURNAME Sinclair, David A.
ALTERNATIVE NAMES Sinclair, David Andrew (full name)
BRIEF DESCRIPTION Australian biologist and professor of genetics
DATE OF BIRTH June 26, 1969
PLACE OF BIRTH Sydney , Australia