Denis Jourdanet

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Denis Jourdanet

Denis Jourdanet (born May 1, 1815 in Juillan , Hautes-Pyrénées department , † May 6, 1892 in Paris ) was a French doctor and physiologist .

Short biography

Jourdanet undertook a research trip to South America in the 1860s as an employee of Paul Bert . In the process, important knowledge was gained about the effects of air pressure on the human body. Jourdanet was the first to establish a connection between the reduced oxygen tension in body tissue (known as hypoxia ) and the simultaneous increased production of red blood cells ( erythrocytes ). He realized that the symptoms of altitude sickness observed in mountain climbers in the Andes and the symptoms of classic anemia can be traced back to the same cause. Jourdanet's work provided the basis for the theory of a humoral factor responsible for the production of erythrocytes. Almost a century after Jourdanet, this factor was identified as erythropoietin by Allan Jacob Erslev and Eugene Goldwasser .

literature

  • Jourdanet D. (1863), De l'anemie des altitudes et de l'anemie en general dans ses reports avec la pression del l'atmosphere . Balliere, Paris.
  • Bert P. (1878), La Pression Barometrique. Recherches de Physiology Experimental. Masson, Paris.

Web links