Disodium malonate

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Structural formula
Structural formula of disodium malonate
General
Surname Disodium malonate
other names

Sodium malonate

Molecular formula CH 2 (COONa) 2
Brief description

white solid

External identifiers / databases
CAS number
  • 141-95-7
  • 26522-85-0 (monohydrate)
  • 132499-82-2 (hydrate)
EC number 205-514-0
ECHA InfoCard 100.005.013
PubChem 8865
Wikidata Q2211758
properties
Molar mass 148.03 g mol −1
Physical state

firmly

density

2.08 g cm −3

solubility

soluble in water (148 g l −1 at 20 ° C)

safety instructions
GHS labeling of hazardous substances
no GHS pictograms
H and P phrases H: no H-phrases
P: no P-phrases
Toxicological data

1100 mg kg −1 ( LD 50 ,  rat ,  ip )

As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Disodium malonate is a chemical compound from the group of malonic acid salts , more precisely the disodium salt of malonic acid.

properties

Disodium malonate is a white solid that is readily soluble in water.

use

Disodium malonate is used to make malonic acid esters. It is also used as an aid for the crystallization of viruses and proteins and for the production of buffer solutions .

Individual evidence

  1. ↑ a b c d e f g Data sheet Sodium malonate dibasic, ≥97.0% (NT) from Sigma-Aldrich , accessed on July 8, 2014 ( PDF ).
  2. ^ KD Pathak, BV Bhide: Molecular polarization in solids . In: Journal of the Indian Chemical Society . tape 30 , 1953, pp. 47 ( books.google.de - limited preview).
  3. ↑ Patent EP1026148 : Process for the production of malonic acid esters. Registered on January 7, 2000 , published on May 7, 2003 , applicant: Lonza AG, inventor: Paul Hanselmann, Stefan Hildbrand. ‌
  4. ↑ Alexander Mcpherson: A comparison of salts for the crystallization of macromolecules . In: Protein Science . tape 10 , no. 2 , February 2001, p. 418-422 , doi : 10.1110 / ps.32001 .
  5. ^ Roger G. Bates, Walter J. Hamer, George G. Manov, SF Acree: Provisional pH values ​​for certain standard buffer solutions . In: Journal of Research of the National Bureau of Standards . tape 29 , no. 3 , September 1942, p. 183 , doi : 10.6028 / jres.029.008 ( nvlpubs.nist.gov [PDF]).