Dirk Bootsma
Dirk Bootsma (* 1936 ) is a Dutch geneticist.
Bootsma studied biology at Utrecht University and received her PhD from Leiden University in 1965 . He then worked in the Department of Cell Biology and Genetics at Erasmus University Rotterdam , where he became Professor of Genetics in 1969. In the early 1970s, after the availability of recombinant DNA technology , he got into gene mapping , but then turned to DNA repair .
In 1982 he and his group discovered the cause of chronic myelogenous leukemia in the fact that two broken chromosomes (9 and 22) were incorrectly repaired by adding the parts to the other chromosome ( Philadelphia chromosome ).
The investigation into the hereditary disease Xeroderma pigmentosum gave him new insights into the repair of nucleotide excisions . In 1984 he and his group succeeded in cloning the enzyme ERCC1, which is involved in the repair .
In 1995 he received the Louis Jeantet Prize with Jan Hoeijmakers , who was also his successor as professor in Rotterdam. He is a member of the Royal Netherlands Academy of Sciences , Academia Europaea and the European Molecular Biology Organization . In 2000 he received the Baschirotto Prize from the European Society of Human Genetics.
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| personal data | |
|---|---|
| SURNAME | Bootsma, Dirk |
| BRIEF DESCRIPTION | Dutch geneticist |
| DATE OF BIRTH | 1936 |