Divinyl sulfone

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Structural formula
Structural formula of divinyl sulfone
General
Surname Divinyl sulfone
other names

Vinyl sulfone

Molecular formula C 4 H 6 O 2 S
External identifiers / databases
CAS number 77-77-0
EC number 201-057-6
ECHA InfoCard 100,000,962
PubChem 6496
Wikidata Q27104812
properties
Molar mass 118.15 g mol −1
density

1.177 g cm −3 (25 ° C)

Melting point

−26 ° C

boiling point

234 ° C

Refractive index

1.476

safety instructions
GHS labeling of hazardous substances
05 - Corrosive 06 - Toxic or very toxic

danger

H and P phrases H: 300 + 310-315-318-335
P: 280-301 + 310 + 330-302 + 352-305 + 351 + 338 + 310
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

Divinyl sulfone is a coupling reagent from the group of vinyl sulfones . It is used for cross-linking of peptides used. It is also used to immobilize peptides on silica .

Individual evidence

  1. ↑ a b c d e f g Data sheet Divinyl sulfone, contains <650 ppm hydroquinone as inhibitor, 97% from Sigma-Aldrich , accessed on October 22, 2016 ( PDF ).
  2. ↑ J. Morales-Sanfrutos, FJ Lopez-Jaramillo, MA Elremaily, F. Hernández-Mateo, F. Santoyo-Gonzalez: Divinyl sulfone cross-linked cyclodextrin-based polymeric materials: synthesis and applications as sorbents and encapsulating agents. In: Molecules . Volume 20, number 3, February 2015, pp. 3565-3581, doi : 10.3390 / molecules20033565 , PMID 25706758 .
  3. ↑ H. Wang, F. Cheng, W. Shen, G. Cheng, J. Zhao, W. Peng, J. Qu: Amino acid-based anti-fouling functionalization of silica nanoparticles using divinyl sulfone. In: Acta Biomaterialia . Volume 40, August 2016, pp. 273-281, doi : 10.1016 / j.actbio.2016.03.035 , PMID 27032480 .