Dyclonine

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Structural formula
Structural formula of dyclonine
General
Non-proprietary name Dyclonine
other names
  • 1- (4-Butoxyphenyl) -3-piperidin-1-ylpropan-1-one ( IUPAC )
  • 4'-butoxy-3-piperidinopropiophenone
Molecular formula C 18 H 27 NO 2
External identifiers / databases
CAS number
PubChem 3180
ChemSpider 3068
DrugBank DB00645
Wikidata Q425386
Drug information
ATC code
Drug class

Local anesthetics

properties
Molar mass 289.41 g · mol -1
safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS labeling of hazardous substances
05 - Corrosive 06 - Toxic or very toxic

danger

H and P phrases H: 301-315-318-335
P: 261-280-301 + 310-305 + 351 + 338
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Dyclonin is a local anesthetic that can be used to anesthetize mucous membranes before medical examinations and procedures. It is also found in lozenges and sprays for the throat and pharynx. Dyclonin can also be used to suppress the gag reflex .

Manufacturing

Dyclonin is produced from 4-butoxy acetophenone , paraformaldehyde and piperidine hydrochloride by the Mannich reaction .

Individual evidence

  1. ↑ a b Data sheet 4′-butoxy-3-piperidinopropiophenone hydrochloride from Sigma-Aldrich , accessed on April 8, 2016 ( PDF ).
  2. ↑ Eberhard Schröder, Clemens Rufer, Ralph Schmiechen, Arzneimittelchemie I, Georg Thieme Verlag 1976, ISBN 3-13-520601-7 .