Emanuel Gil-Av

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Emanuel Gil-Av

Emanuel Gil-Av (born August 7, 1916 in Penza , Russian Empire , † March 24, 1996 ) was an Israeli chemist. The focus of his work was in the field of chiral chromatography for the separation of enantiomers .

life and work

Emanuel Gil-Av was born in 1916 in Penza , Russian Empire . After the father's death in 1928, the family moved to Tel-Aviv , where he attended high school. Gil-Av then studied chemistry at the University of Strasbourg . In 1940 he fled to England, where he worked at Chaim Weizmann's chemical laboratory and later at Petrochemical Ltd. Worked in Manchester . After the war he moved to the Weizmann Institute of Science , where he received his doctorate in 1951 in the work group of Ernst David Bergmann .

In collaboration with the working group for peptide chemistry , he developed methods for the chiral gas chromatographic separation of chiral molecules such as α- amino acids . By coating a gas chromatographic column with N -trifluoroacetyl- L- isoleucine lauryl ester in diethyl ether , he succeeded in 1966 in producing a chiral stationary phase for the first time , with which the enantiomeric separation of racemic D , L -amino acids as N -trifluoroacetyl- O -alkyl ester derivative succeeded. Racemates , which can enter into an enantioselective interaction via hydrogen bonds with the stationary phase, could for the first time be separated by gas chromatography.

Prices

Together with the French chemist Jean Jacques, Gil-Av was the first recipient to be awarded the Chirality Medal by the Società Chimica Italiana .

literature

Individual evidence

  1. ^ Chirality Medal Page .
personal data
SURNAME Gil-Av, Emanuel
ALTERNATIVE NAMES גיל-אב, עמנואל
BRIEF DESCRIPTION Israeli chemist
DATE OF BIRTH August 7, 1916
PLACE OF BIRTH Penza , Russian Empire
DATE OF DEATH March 24, 1996