Emanuel Gil-Av
Emanuel Gil-Av (born August 7, 1916 in Penza , Russian Empire , † March 24, 1996 ) was an Israeli chemist. The focus of his work was in the field of chiral chromatography for the separation of enantiomers .
life and work
Emanuel Gil-Av was born in 1916 in Penza , Russian Empire . After the father's death in 1928, the family moved to Tel-Aviv , where he attended high school. Gil-Av then studied chemistry at the University of Strasbourg . In 1940 he fled to England, where he worked at Chaim Weizmann's chemical laboratory and later at Petrochemical Ltd. Worked in Manchester . After the war he moved to the Weizmann Institute of Science , where he received his doctorate in 1951 in the work group of Ernst David Bergmann .
In collaboration with the working group for peptide chemistry , he developed methods for the chiral gas chromatographic separation of chiral molecules such as α- amino acids . By coating a gas chromatographic column with N -trifluoroacetyl- L- isoleucine lauryl ester in diethyl ether , he succeeded in 1966 in producing a chiral stationary phase for the first time , with which the enantiomeric separation of racemic D , L -amino acids as N -trifluoroacetyl- O -alkyl ester derivative succeeded. Racemates , which can enter into an enantioselective interaction via hydrogen bonds with the stationary phase, could for the first time be separated by gas chromatography.
Prices
Together with the French chemist Jean Jacques, Gil-Av was the first recipient to be awarded the Chirality Medal by the Società Chimica Italiana .
literature
- Nelu Grinberg: Emanuel Gil-Av (1916-1996): A man with a legacy , In: Chirality . , 1998; 10 (5): 372- doi : 10.1002 / (SICI) 1520-636X (1998) 10: 5 <373 :: AID-CHIR2> 3.0.CO; 2-7
- Volker Schurig : In Memoriam - Emanuel Gil-Av. In: Journal of High Resolution Chromatography . 19, 1996, p. 462, doi : 10.1002 / jhrc.1240190808 .
- Volker Schurig: On the Centenary of Emanuel Gil-Av, Former Professor of the Weizmann Institute of Science and Pioneer of Enantioselective Chromatography , Isr. J. Chem. 56 (2016) 890–906, doi: 10.1002 / ijch.201600015 .
Individual evidence
personal data | |
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SURNAME | Gil-Av, Emanuel |
ALTERNATIVE NAMES | גיל-אב, עמנואל |
BRIEF DESCRIPTION | Israeli chemist |
DATE OF BIRTH | August 7, 1916 |
PLACE OF BIRTH | Penza , Russian Empire |
DATE OF DEATH | March 24, 1996 |