Fluoroanisoles

Fluoroanisoles
Surname	2-fluoroanisole	3-fluoroanisole	4-fluoroanisole
other names	o -fluoroanisole	m -fluoroanisole	p -fluoroanisole
Structural formula
CAS number	321-28-8	456-49-5	459-60-9
PubChem	67576	9975	9987
ECHA InfoCard	100.005.715	100.006.608	100.006.633
Molecular formula	C 7 H 7 FO
Molar mass	126.13 g mol −1
Physical state	liquid
Melting point	−39 ° C	−35 ° C	−45 ° C
boiling point	154-155 ° C	158-159 ° C	157 ° C
GHS labeling	Caution
H and P phrases	226
	no EUH phrases
	no P-phrases

The fluoroanisoles form a group of substances in chemistry that is derived from both anisole and fluorobenzene . The structure consists of a benzene ring with an attached methoxy group  (–OCH ₃ ) and fluorine  (–F) as substituents . Their different arrangements ( ortho , meta or para ) result in three constitutional isomers with the empirical formula C ₇ H ₇ FO.

presentation

Fluoroanisoles can be prepared from the fluorophenols by etherification with dimethyl sulfate .

properties

The introduction of the fluorine atom changes the melting and boiling points only slightly compared to anisole (−37 ° C and 154 ° C).

Individual evidence

1. ↑ ^{a b c} data sheet 2-fluoroanisole from Sigma-Aldrich , accessed on May 25, 2011 ( PDF ).
2. ↑ ^{a b} Alfa Aesar catalog 2008/09, p. 978.
3. ↑ ^{a b c} Data sheet 4-Fluoroanisole from Sigma-Aldrich , accessed on May 25, 2011 ( PDF ).
4. ↑ Data sheet 3-Fluoroanisole from Sigma-Aldrich , accessed on May 25, 2011 ( PDF ).
5. ↑ ^{a b} Entry on anisole in the GESTIS substance database of the IFA , accessed on December 25, 2019(JavaScript required) .