Gallant
| Gallant | ||
|---|---|---|
| Properties of human protein | ||
| Mass / length primary structure | 30 aa; 3.16 kDa | |
| Precursor | (123 aa; 13.3 kDa) | |
| Identifier | ||
| Gene names | GAL ; GALN; GLNN; MGC40167 | |
| External IDs | ||
| Occurrence | ||
| Parent taxon | Euteleostomi | |
| Orthologue | ||
| human | mouse | |
| Entrez | 51083 | 14419 |
| Ensemble | ENSG00000069482 | ENSMUSG00000024907 |
| UniProt | P22466 | Q3V002 |
| Refseq (mRNA) | NM_015973 | NM_010253 |
| Refseq (protein) | NP_057057 | NP_034383 |
| Gene locus | Chr 11: 68.21 - 68.22 Mb | Chr 19: 3.41 - 3.41 Mb |
| PubMed search | 51083 |
14419
|
Galanin is a neuropeptide found in the central and peripheral nervous systems. The galanin of humans consists of 30 amino acids .
In the central nervous system, galanin is involved in regulating the release of various neurotransmitters . Its regulatory influence on acetylcholine release has been linked to its involvement in the pathogenesis of Alzheimer's disease .
Galanin may also be involved in various other neurological effects such as: B. the inhibition of epileptic seizures and pain involved.
In the peripheral nervous system, this neuropeptide influences the motility of the gastrointestinal tract .
In addition, Galanin can act on the endocrine system by controlling the release of prolactin , LH and somatotropin . These effects of galanin are mediated by three different G-protein-coupled receptors : GALR1 - GALR3.