Gerhard Klebe

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Gerhard Klebe (* 1954 in Frankfurt am Main ) is a German chemist ( pharmaceutical chemistry , crystallography ) and professor at the Philipps University of Marburg .

Klebe studied chemistry at the Goethe University in Frankfurt am Main , where he received his diploma in 1977 and received his doctorate in 1982 under Karl Hensen (representation and structure elucidation of chelate complexes of boron and silicon: tetracoordinated boron and pentacoordinated silicon). In 1981 he was at the Institut Laue-Langevin in Grenoble, where he dealt with neutron scattering and difference electron determination in crystallography. As a postdoctoral fellow he was at the Institute for Crystallography at the University of Frankfurt with Hartmut Fueß and at the University of Bern with Hans Beat Bürgi . From 1984 he was at the main laboratory at BASFin Ludwigshafen in the field of active ingredient design and crystallography. In 1991 he completed his habilitation at the University of Heidelberg under Richard Neidlein (contributions to the correlation of structure and property - a view from a crystallographic perspective) and then had a teaching position in Heidelberg, before becoming Professor of Pharmaceutical Chemistry in Marburg in 1996.

Klebe deals with structure-reactivity correlations, conformational and pharmacophore analyzes as well as 3D QSAR methods. His book on active ingredient design with Hans-Joachim Böhm ( Hoffmann-La Roche ) and Hugo Kubinyi (BASF) received the 1999 literature prize from the Fonds der Chemischen Industrie .

He was editor of the Journal of Computer-Aided Molecular Design and served on the Council of Cambridge Crystallographic Data Center.

Fonts

  • with Hans-Joachim Böhm, Hugo Kubinyi: "Active substance design", Spektrum Akademischer Verlag 2002, ISBN 978-3827400123
  • "Active substance design: Design and effects of medicinal substances", 2nd edition, Spektrum Akademischer Verlag 2009, ISBN 978-3-8274-2213-2

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personal data
SURNAME Klebe, Gerhard
BRIEF DESCRIPTION German chemist
DATE OF BIRTH 1954
PLACE OF BIRTH Frankfurt am Mainl