Glycerol monostearate

Glycerin monostearate is a mixture of monofatty acid esters of glycerin , mainly stearic and palmitic acid , with varying amounts of di- and tri-fatty acid esters of glycerin and contains at least 40% glycerin-1- (palmitate, stearate).

Extraction and presentation

Glycerin monostearate is formed when mixtures of stearic and palmitic acids are esterified with glycerin.

properties

Glycerol
oleic
glyceryl
monostearin
E 471

Surname

1-glycerol monostearate

2-glycerol monostearate

Structural formula

CAS number

123-94-4

621-61-4

31566-31-1 (mixture of isomers)

PubChem

79075

C ₂₁ H ₄₂ O ₄

358.56 g mol ⁻¹

firmly

Brief description

white to yellow solid

Melting point

56-58 ° C

density

0.92-0.93 g cm ^-3

solubility

practically insoluble in water (<1 mg l ⁻¹ at 20 ° C)

GHS
labeling

no GHS pictograms

H and P phrases

no H-phrases

no P-phrases

Glycerin monostearate is a white, solid, waxy mass that is greasy to the touch, with a melting point not below 55 ° C. It is practically insoluble in water but soluble in diethyl ether.

use

Glycerine monostearate is used in pharmacy as a non-ionic emulsifier, consistency enhancer for semi-solid preparations, glidants and lubricants in tablet production, anti-stick and dispersant in coating preparations, additive to slow-release drugs. Otherwise, the main area of application is in the food sector as a declarable additive.

Individual evidence

↑ ^a ^b ^c Franz v. Bruchhausen, Gerd Dannhardt, Siegfried Ebel, August W. Frahm, Eberhard Hackenthal, Ulrike Holzgrabe: Hagers Handbook of Pharmaceutical Practice Volume 8: Substances EO . Springer-Verlag, 2013, ISBN 978-3-642-57994-3 , pp. 368 ( limited preview in Google Book search).
↑ Ernst Steinegger, Rudolf Hansel: Pharmakognosie . Springer-Verlag, 2013, ISBN 978-3-662-09267-5 , pp. 53 ( limited preview in Google Book search).
↑ ^a ^b ^c ^d ^e Entry on glycerine monostearate in the GESTIS substance database of the IFA , accessed on December 8, 2018(JavaScript required) .

[Franz_v._Bruchhausen-1] Franz v. Bruchhausen, Gerd Dannhardt, Siegfried Ebel, August W. Frahm, Eberhard Hackenthal, Ulrike Holzgrabe: Hagers Handbook of Pharmaceutical Practice Volume 8: Substances EO . Springer-Verlag, 2013, ISBN 978-3-642-57994-3 , pp. 368 ( limited preview in Google Book search).

[Ernst_Steinegger,_Rudolf_Hänsel-2] Ernst Steinegger, Rudolf Hansel: Pharmakognosie . Springer-Verlag, 2013, ISBN 978-3-662-09267-5 , pp. 53 ( limited preview in Google Book search).

[GESTIS-3] Entry on glycerine monostearate in the GESTIS substance database of the IFA , accessed on December 8, 2018(JavaScript required) .