Hans Andersag
Hans Andersag (born February 16, 1902 in Lana ( Meran ); † August 10, 1955 in Wuppertal ) was a German chemist .
Life
He was an Italian citizen, did his doctorate in chemical engineering and from 1928 worked at Bayer in the main laboratory in Elberfeld .
In 1934 Andersag succeeded in discovering chloroquine (called Resochin), a very effective active ingredient against malaria , in the Bayer laboratory in Wuppertal-Elberfeld (at the time part of I. G. Farbenindustrie AG ). Chloroquine has long been the most widely used drug used in the prevention and treatment of malaria. However, its benefits as a malaria remedy were not discovered until the United States during World War II, and it was widely used after the war. At Bayer, this use was discontinued due to suspected toxicity and instead Sontochin (the methylized form of chloroquine) was developed.
Independently of Robert R. Williams , he synthesized vitamin B1 with Kurt Westphal in 1936 . Andersag also succeeded in the first synthesis of vitamin B6 , together with Richard Kuhn , Kurt Westphal and Gerhard Wendt.
literature
- K. Krafts, E. Hempelmann, A. Skórska-Stania: From methylene blue to chloroquine: a brief review of the development of an antimalarial therapy . Parasitology Research, 11/1, 2012, pp. 1-6
- HB Dünschede: Tropical medicine research at Bayer . In: H. Schadewaldt (Ed.): Düsseldorfer work on the history of medicine . 1971
- Entry in Winfried Pötsch, Annelore Fischer, Wolfgang Müller: Lexicon of important chemists, Harri Deutsch 1989
Web links
- Facsimile of the protocol of the first synthesis of chloroquine
| personal data | |
|---|---|
| SURNAME | Andersag, Hans |
| BRIEF DESCRIPTION | German scientist |
| DATE OF BIRTH | February 16, 1902 |
| PLACE OF BIRTH | Lana , Merano |
| DATE OF DEATH | August 10, 1955 |
| Place of death | Wuppertal |