Hans Robert Kalbitzer

Hans Robert Kalbitzer (born April 10, 1949 in Ludwigshafen am Rhein ) is a German physicist , medic and professor at the University of Regensburg .

life and work

Hans Robert Kalbitzer was born on April 10, 1949, the son of Dorothea Wentzel and Hans Kalbitzer. He attended the Luitpold School from 1955 to 1959 and the Theodor-Heuss-Gymnasium in Ludwigshafen am Rhein from 1959 to 1967 and studied medicine from 1967 to 1971 and physics from 1968 to 1971 at the University of Göttingen . He then moved to Heidelberg University in 1971 , where he continued his studies. In 1973 he passed the state examination in medicine there and graduated with a diploma in physics in 1976. In addition, he obtained the degree of Dr. med. for a doctoral thesis entitled The Binding of Calcium and Magnesium Ions to Vesicles of the Sarcoplasmic Reticulum: A Manganese (II) Electron Spin Resonance Study . After working as a medical assistant at the university clinics in Heidelberg and Mannheim, he received his license to practice medicine in 1978 . From 1977 to 1986 he worked as a group leader in the Department of Molecular Physics at the Max Planck Institute for Medical Research , where he received his doctorate in 1981 with nuclear magnetic resonance examinations on factor IIIlac (now EIIAlac) of the phosphoenolpyruvate-dependent phosphotransferase system at the Faculty of Physics at Heidelberg University. He then completed his habilitation at the Faculty of Medicine in biochemistry with work on ESR and NMR studies on the structure and mechanism of phosphate-transferring enzymes and transport proteins and received the license to teach ( venia legendi ) in biochemistry in 1984 . From 1987 to 1996 he worked as a freelance scientist in the Department of Biophysics of Ken Holmes at the Max Planck Institute for Medical Research, where he was additionally authorized to teach biophysics in 1995 at the Faculty of Biology at Heidelberg University. Since 1997 he has been a professor at the University of Regensburg and until 2014 headed the chair for biophysics at the Institute for Biophysics and Physical Biochemistry in the Faculty of Biology and Preclinical Medicine, where he was also dean from 2003 to 2006 . Since 2011 he has been director of the Center for Magnetic Resonance in Chemistry and Biomedicine (CMRCB) at the University of Regensburg. Together with Fritz Huber and Werner Kremer, he is co-founder of Lipofit GmbH (now numares AG, Regensburg) and founder of Kalbitzer-Innovations UG.
Kalbitzer works in the field of biochemistry and nuclear magnetic resonance spectroscopy (NMR). In particular, the use of high pressures in NMR was promoted by him and led to the identification and structural elucidation of conformers of the medically important macromolecule Ras, which play an important role in protein-protein recognition. They are the basis of intrinsic allostery , which enables new approaches and points of attack in pharmaceutical research and thus can have a lasting influence on cancer research and cancer treatment.

Kalbitzer has published more than 250 papers and 5 patents so far. Since 1994 he has been with Ulrike Kalbitzer, geb. Stind, married and have two children.
Kalbitzer is a member of various scientific organizations, including the German Society for Biochemistry and Molecular Biology (GBM) and the German Society of Chemistry (GDCh).

• 1993 Visiting scientist, Stanford University, Stanford, California, USA
• 1997 JSSP Award, Kobe University Kobe, Japan
• 2001 Visiting scientist, Protein Design Group CNB-CSIC, Cantoblanco, Spain
• 2007 Visiting scientist, University of California, Berkeley, California, USA
• 2011 HFSP Award

Web links

• Kalbitzer's website at the University of Regensburg